Anne-Marie Coelho

No ORCID on file · 2 papers in corpus · active 2019-2021

Study types

  • article 2

Condition tags

  • endometriosis 2
  • dyspareunia 1
article 2021
Eliapixant is a selective P2X3 receptor antagonist for the treatment of disorders associated with hypersensitive nerve fibers
Scientific reports ·doi:10.1038/s41598-021-99177-0

ATP-dependent P2X3 receptors play a crucial role in the sensitization of nerve fibers and pathological pain pathways. They are also involved in pathways triggering cough and may contribute to the pathophysiology of endometriosis and overact…

article 2019
Discovery and optimization of pyridyl-cycloalkyl-carboxylic acids as inhibitors of microsomal prostaglandin E synthase-1 for the treatment of endometriosis
Bioorganic & medicinal chemistry letters ·doi:10.1016/j.bmcl.2019.07.007