Minuo Yin

ORCID: 0000-0003-1351-0635 · 4 papers in corpus
article 2025
Harmine inhibits oxidative phosphorylation, thus regulating the polarization of macrophages mediated by extracellular adenosine in endometriosis
Human Reproduction ·doi:10.1093/humrep/deaf130

STUDY QUESTION: Can harmine mitigate endometriosis by modulating oxidative phosphorylation (OXPHOS) suppression and macrophage polarization? SUMMARY ANSWER: Harmine induces apoptosis in endometriotic lesions by inhibiting OXPHOS while also…

article 2021
Target identification and drug discovery by data-driven hypothesis and experimental validation in ovarian endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2021.01.027

ObjectiveTo identify targets and discover drugs for ovarian endometriosis (OE) DESIGN: A basic study based on a data-driven hypothesis and experimental validation SETTING: Center for Reproductive Medicine PATIENT(S)/ANIMAL(S): Fourteen pati…

article 2020
Erastin induces ferroptosis via ferroportin-mediated iron accumulation in endometriosis
Human Reproduction ·doi:10.1093/humrep/deaa363

STUDY QUESTION: Could erastin activate ferroptosis to regress endometriotic lesions? SUMMARY ANSWER: Erastin could induce ferroptosis to regress endometriotic lesions in endometriosis. WHAT IS KNOWN ALREADY: Ectopic endometrial stromal cell…

article 2018
NR4A1 is Involved in Fibrogenesis in Ovarian Endometriosis
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology ·doi:10.1159/000488838

BACKGROUND/AIMS: Excess fibrosis may lead to chronic pain, scarring, and infertility as endometriosis develops and progresses. The pathogenesis of endometriosis has been linked to transforming growth factor-β (TGF-β), the most potent promot…