Hirayama M

No ORCID on file · 2 papers in corpus · active 2024-2026

Study types

  • other 1
  • rct 1

Condition tags

  • endometriosis 2
  • chronic_pelvic_pain 1
other 2026
Impact of estetrol and drospirenone combination therapy on alleviation of the pelvic pain of endometriosis: a randomized control trial
F&S reports ·doi:10.1016/j.xfre.2025.12.002

OBJECTIVE: To study the impact of estetrol (E4), a novel native estrogen with selective tissue activity, on endometriosis-associated pelvic pain (EAPP) and global impressions of endometriosis pain. DESIGN: Multicenter, randomized, open-lab…

rct 2024
Efficacy and safety of the combination of estetrol 15 mg/drospirenone 3 mg in a cyclic regimen for the treatment of endometriosis-associated pain and objective gynecological findings: a multicenter, placebo-controlled, double-blind, randomized study
Fertility and sterility ·doi:10.1016/j.fertnstert.2024.07.011

OBJECTIVE: To evaluate the efficacy and safety of 24-week cyclic administration of estetrol (E4) (15 mg)/drospirenone (DRSP) (3 mg) in Japanese patients with endometriosis. DESIGN: A 24-week, multicenter, randomized, double-blind, placebo-…