M Jeljeli

No ORCID on file · 4 papers in corpus · active 2019-2024

Study types

  • article 2
  • other 1
  • review 1

Condition tags

  • adenomyosis 3
  • endometriosis 2
other 2024
Reduced fertility in an adenomyosis mouse model is associated with an altered immune profile in the uterus during the implantation period
Human Reproduction ·doi:10.1093/humrep/dead246

STUDY QUESTION: Does a reduction in fertility and/or systemic immune cell change occur during the early implantation period in a mouse model of adenomyosis? SUMMARY ANSWER: A reduction in fertility was observed in mice with adenomyosis, co…

article 2021
Immune cells and Notch1 signaling appear to drive the epithelial to mesenchymal transition in the development of adenomyosis in mice
Molecular human reproduction ·doi:10.1093/molehr/gaab053

The epithelial to mesenchymal transition (EMT) has been implicated in the development of adenomyosis, along with dysregulated immune responses. Inflammation potentially induces Notch signaling, which could promote this EMT. The objective of…

review 2020
Immunological changes associated with adenomyosis: a systematic review
Human reproduction update ·doi:10.1093/humupd/dmaa038

BACKGROUND: Adenomyosis is a benign gynecological disorder associated with subfertility, pelvic pain and abnormal uterine bleeding that have significant consequences for the health and quality of life of women. Histologically, it is defined…

article 2019
B lymphocytes inactivation by Ibrutinib limits endometriosis progression in mice
Human Reproduction ·doi:10.1093/humrep/dez071

STUDY QUESTION: What are the effects of B lymphocyte inactivation or depletion on the progression of endometriosis? SUMMARY ANSWER: Skewing activated B cells toward regulatory B cells (Bregs) by Bruton's tyrosine kinase (Btk) inhibition usi…