Extracellular Vesicles (EVs) are small, membrane-bound particles released by cells into biological fluids, where they function as mediators of intercellular communication. These vesicles transport a diverse array of bioactive molecules, inc…
Microorganisms play an important role in regulating various biological processes in our bodies. In women, abnormal changes in the reproductive tract microbiome are associated with various gynecological diseases and infertility. Recent studi…
The human endometrium and embryo both produce microRNAs (miRNAs), which are involved in various physiological activities. Accumulating evident suggested that endometrial miRNAs are regulated by steroid hormones that modulate endometrial fun…
Synchronized crosstalk between the embryo and endometrium during the periconception period is integral to pregnancy establishment. Increasing evidence suggests that the exchange of extracellular vesicles (EVs) of both embryonic and endometr…
The mammalian reproduction is a process of controlled cellular growth and development regulated by constant communication between the gametes, the subsequent embryo and the maternal system. Extracellular vesicles (EVs) are involved in these…
During implantation, a symphony of interaction between the trophoblast originated from the trophectoderm of the implanting blastocyst and the endometrium leads to a successful pregnancy. Defective interaction between the trophoblast and end…
Ectopic pregnancy (EP) occurs when the embryo fails to transit to the uterus and attach to the luminal epithelium of the Fallopian tube (FT). Tubal EP is a common gynecological emergency and more than 95% of EP occurs in the ampullary regio…