Jiaxin Zhang

No ORCID on file · 9 papers in corpus · active 2021-2026

Study types

  • article 5
  • other 2
  • preprint 1

Condition tags

  • endometriosis 8
  • infertility 2
  • adenomyosis 1
article 2026
Hypoxia-mediated epigenetic silencing of YTHDF2 promotes endometriosis progression via the NFE2L1-NF-κB axis
International journal of biological macromolecules ·doi:10.1016/j.ijbiomac.2026.152621

Endometriosis (EMs) is a chronic inflammatory disease characterized by ectopic growth of endometrial-like tissues. N6-methyladenosine (m6A) modification regulates diverse cellular processes, yet its role in EMs remains unclear. Here, we sho…

other 2025
Association of Sleep Traits, Physical Activity, and Sedentary Leisure Behavior With Female Reproductive Health: A Two-Sample Mendelian Randomization Analysis
International journal of women's health ·doi:10.2147/IJWH.S492065

PURPOSE: Living habits affect female endocrine function and fertility, along with aging and other life factors. Because of this, female reproductive health can be promoted through living habit adjustment. METHODS: We used two-sample Mendel…

other 2025
Cyclooxygenase 2 overexpression suppresses Smad3 and augments ERK1/2 signaling activated by TGFβ1 in endometrial stromal cells: A novel insight into endometriosis pathogenesis
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2025.112470

RESEARCH QUESTION: To investigate the underlying mechanisms driving the opposing effects of transforming growth factor-beta 1 (TGFβ1) on the proliferation of control (CESCs) and ectopic (EESCs) endometrial stromal cells. DESIGN: Cell proli…

article 2025
Identification and validation of a novel machine learning model for predicting severe pelvic endometriosis: A retrospective study
Scientific reports ·doi:10.1038/s41598-025-96093-5

This study aimed to explore potential risk factors for severe endometriosis and to develop a model to predict the risk of severe endometriosis. A total of 308 patients with endometriosis were analyzed. Least absolute shrinkage and selection…

article 2024
Causal Link between Gut Microbiota and Infertility: A Two-sample Bidirectional Mendelian Randomization Study
Current medical science ·doi:10.1007/s11596-024-2931-x

OBJECTIVE: To investigate the associations of the gut microbiota with reproductive system diseases, including female infertility, male infertility, polycystic ovary syndrome (PCOS), primary ovarian failure, endometriosis, uterine fibroids, …

preprint 2024
Identification and Validation of a Novel Machine Learning Model for Predicting Severe Pelvic Endometriosis: A Retrospective Study
·doi:10.21203/rs.3.rs-5309546/v1

Abstract Background Severe endometriosis significantly impacts the quality of life, particularly in women of reproductive age. Though numerous studies have conducted predictive models with preoperative clinical data for endometriosis, mos…

article 2024
Identification of common diagnostic genes and molecular pathways in endometriosis and systemic lupus erythematosus by machine learning approach and in vitro experiment
International journal of medical sciences ·doi:10.7150/ijms.101754

Growing research suggests that endometriosis and systemic lupus erythematosus (SLE) are both chronic inflammatory diseases and closely related, but no studies have explored their common molecular characteristics and underlying mechanisms. B…

article 2021
Impact of Uterine Adenomyosis on Pregnancy Outcomes in Women Undergoing In Vitro Fertilization Treated With a Long-Term Pituitary Downregulation Protocol
Frontiers in endocrinology ·doi:10.3389/fendo.2021.655803

Background Some studies have demonstrated that adenomyosis patients can achieve a comparable pregnancy outcome with women with normal uteruses, while there is no unanimous conclusion at present. Method We recruited 65 adenomyosis patients a…

2021
Pyrotinib In The Treatment of Women With Advanced HER2- Positive Breast Cancer: A Multicenter, Prospective, Real-World Study
·doi:10.21203/rs.3.rs-505602/v1