de Souza IC

No ORCID on file · 2 papers in corpus · active 2013-2014

Study types

  • article 1

Condition tags

  • dysmenorrhea 1
  • endometriosis 1
  • chronic_pelvic_pain 1
2014
Melatonin analgesia is associated with improvement of the descending endogenous pain-modulating system in fibromyalgia: a phase II, randomized, double-dummy, controlled trial.
BMC pharmacology & toxicology ·doi:10.1186/2050-6511-15-40

BackgroundCentral disinhibition is a mechanism involved in the physiopathology of fibromyalgia. Melatonin can improve sleep quality, pain and pain threshold. We hypothesized that treatment with melatonin alone or in combination with amitrip…

article 2013
Efficacy of melatonin in the treatment of endometriosis: A phase II, randomized, double-blind, placebo-controlled trial
Pain ·doi:10.1016/j.pain.2013.02.025

Endometriosis-associated chronic pelvic pain (EACPP) presents with an intense inflammatory reaction. Melatonin has emerged as an important analgesic, antioxidant, and antiinflammatory agent. This trial investigates the effects of melatonin …