Human endometrium sheds and regenerates each month during the menstrual cycle. N-cadherin+ (CDH2) glandular epithelial progenitors and SUSD2+ mesenchymal stem cells (MSCs) and their niches have been identified, but their signaling interacti…
BackgroundInfertility is an underrecognized disease which affects over 17% of the reproductive age population worldwide. However, availability of, and access to, assisted reproductive technology (ART) is variable across countries. There are…
STUDY QUESTION: Can we develop a prediction model for the chance of a live birth following the transfer of an embryo created using donated oocytes? SUMMARY ANSWER: Three primary models that included patient, past treatment, and cycle chara…
OBJECTIVE: The World Endometriosis Research Foundation established the Endometriosis Phenome and Biobanking Harmonisation Project (EPHect) to create standardized documentation tools (with common data elements) to facilitate the comparison a…
In Australia, endometriosis affects one in nine women and those assigned female at birth. Although endometriosis is more common than conditions such as diabetes, research funding for endometriosis research has historically been low in compa…
PurposeLimited research has been published comparing PIEZO-ICSI with conventional ICSI. While positive effects have been documented in improving fertilization and degeneration, the outcomes in patients with previous poor results from conven…
COVID-19 has led to new obstacles in the care for women with endometriosis. With many centers around the globe temporarily ceasing outpatient appointments, diagnostic imaging for non-acute pelvic pain, surgery for endometriosis, and fertili…
Study questionWhat is the recommended assessment and management of infertile women with polycystic ovary syndrome (PCOS), based on the best available evidence, clinical expertize and consumer preference?Summary answerInternational evidence-…
Study questionDoes melatonin result in a dose-response effect on sleep quality and daytime sleepiness in women undergoing IVF?Summary answerMelatonin, even when given at high doses twice per day, does not cause significant daytime sleepines…
STUDY QUESTION: What is the global consensus on the classification of endometriosis that considers the views of women with endometriosis? SUMMARY ANSWER: We have produced an international consensus statement on the classification of endomet…