A M Sharkey

No ORCID on file · 5 papers in corpus · active 1996-2010

Study types

  • article 5

Condition tags

  • endometriosis 5
  • infertility 2
article 2010
The Endometrial Response to Chorionic Gonadotropin Is Blunted in a Baboon Model of Endometriosis
Endocrinology ·doi:10.1210/en.2010-0275

Endometriosis-associated infertility has a multifactorial etiology. We tested the hypothesis that the endometrial response to the early embryonic signal, human chorionic gonadotropin (hCG), alters over time in a nonhuman primate model of en…

article 2008
Global gene analysis of late secretory phase, eutopic endometrium does not provide the basis for a minimally invasive test of endometriosis
Human Reproduction ·doi:10.1093/humrep/den078

BACKGROUND: Endometriosis occurs in 10% of women and is currently diagnosed by invasive laparoscopic testing. We tested the hypothesis that endometrial gene expression in late secretory phase endometrium differs between patients with and wi…

article 2000
Vascular Endothelial Growth Factor Expression in Human Endometrium Is Regulated by Hypoxia1
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.85.1.6229

Endometrial growth and repair after menstruation are associated with profound angiogenesis. Abnormalities in these processes result in excessive or unpredictable bleeding patterns and are common in many women. It is therefore important to u…

article 1997
Immunolocalization of the apoptosis regulating proteins Bcl-2 and Bax in human endometrium and isolated peritoneal fluid macrophages in endometriosis
Human Reproduction ·doi:10.1093/humrep/12.1.146

Endometriosis, a debilitating disease associated with infertility, is characterized by the prolonged presence of ectopic endometrial tissue and the involvement of activated peritoneal fluid macrophages. Apoptosis, which occurs in both endom…

article 1996
Vascular endothelial growth factor is produced by peritoneal fluid macrophages in endometriosis and is regulated by ovarian steroids.
The Journal of clinical investigation ·doi:10.1172/jci118815

Angiogenesis is important in the pathophysiology of endometriosis, a condition characterized by implantation of ectopic endometrium in the peritoneal cavity. Vascular endothelial growth factor (VEGF) is a potent angiogenic factor involved i…