OBJECTIVE: There is currently no consensus on the risk factors for recurrent ovarian endometrioma after surgery. This study aimed to identify independent risk factors and develop a clinical nomogram to predict postoperative recurrence. MET…
Objective: To develop and compare a random survival forest (RSF) model and a Cox regression model-for predicting postoperative recurrence in patients with ovarian endometrioma. Methods: The primary outcomes of the study were the recurrence …
OBJECTIVE: To explore the regulatory function and mechanism of CXCL14 in endometriosis. METHODS: Quantitative real-time polymerase chain reaction (qRT-PCR) was used to examine the expression of CXCL14 in eutopic and ectopic endometrial str…
Chronic endometritis (CE) is a persistent inflammatory disorder of the endometrium, typically marked by abnormal plasma cell infiltration. It is closely associated with adverse pregnancy outcomes. The pathogenesis of CE involves a complex i…
Ovarian clear cell carcinoma (OCCC) represents a rare and aggressive subtype of epithelial ovarian cancer with distinctive clinical and molecular characteristics. However, the identification, origin, and molecular features of the malignant …
BACKGROUND: Adenomyosis is a uterine disorder closely linked to infertility and adverse pregnancy outcomes. Despite its clinical significance, the mechanisms by which adenomyosis impairs embryo implantation and perinatal outcomes remain inc…
OBJECTIVE: Endometriosis increases ovarian cancer (OC) risk through genetic mutations, chronic inflammation, and hormonal dysregulation, yet the underlying molecular pathways remain underexplored. This study aims to identify endometriosis-a…
Female infertility represents a significant global medical concern, attributable to a spectrum of disorders affecting the reproductive system, which encompasses premature ovarian insufficiency (POI), polycystic ovary syndrome (PCOS), Asherm…
OBJECTIVE: To investigate whether the 115T/C, 240A/G and 1531C/T polymorphisms of CYP19 gene are associated with the risk of moderate/severe endometriosis. METHODS: Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFL…