BACKGROUND: In 2018 the Australian Government launched the world's first National Action Plan for Endometriosis (NAPE). Of its three priorities 'Priority 1' was 'Education and Awareness'. In response, the Pelvic Pain Foundation of Australia…
BACKGROUND: An expectation that pelvic pain should be 'visible' at laparoscopy can lead to disappointment for patients and confusion among health practitioners when no abnormalities are found. OBJECTIVE: This article outlines an approach fo…
Persistent pelvic pain is a significant healthcare concern among adolescents; however adolescents often have poor health literacy regarding their pain. Current school curricula fail to specifically address pelvic pain and management strateg…
BackgroundDysmenorrhoea-Related Pelvic Pain (DRPP) is a common condition, which may or may not include bladder-related symptoms. Primary health care practitioners (PHCP) rely heavily on language for diagnosis of DRPP-related conditions. How…
Endometriosis is a polygenic, estrogen-dependent, inflammatory disorder of uncertain aetiology associated with pain, infertility and reduced quality of life. While the positive association between endometriosis and estrogen is established, …
The intriguing relationship between androgens, endometriosis and chronic pain continues to unfold. Determining this relationship is of crucial importance to gynecologists managing people with these conditions, as common treatments dramatica…
OBJECTIVE: To establish which psychological therapies mental health professionals use with reference to the treatment of women with persistent pelvic pain conditions. This research investigates overall therapies and specific techniques that…
PurposeWomen bear a disproportionate burden of persistent pain conditions when compared to men. To determine whether the hormonal environment affects the clinical experience of pain, as measured by the days per month of pelvic pain (DPelvic…
OBJECTIVE: Establishing predictors of mental health outcomes is a crucial precursor to the development and assessment of psychological interventions for women with chronic pelvic pain (CPP). The objective of this study was to identify predi…
OBJECTIVE: CPP affects approximately 15% of women worldwide and has significant psychological, physical and financial impact on the lives of sufferers. Psychological interventions are often recommended as adjuncts to medical treatment for w…
PurposeDysmenorrhea is a common disorder that substantially disrupts the lives of young women. To determine whether there is evidence of activation of the innate immune system in dysmenorrhea and whether the degree of activation may be used…
CONTEXT: Despite extensive searches for novel noninvasive diagnostics, laparoscopy remains the reference test for endometriosis. Circulating miRNAs are purported endometriosis biomarkers; however, the miRNA species and their diagnostic accu…
Chalmers, K. Jane PhD*; Catley, Mark J. PhD†; Evans, Susan F. MBBS‡; Moseley, G. Lorimer DSc, PhD†Author Information
Glial adaptations within the central nervous system are well known to modulate central sensitization and pain. Recently, it has been suggested that activity of glial-related proinflammatory cytokines may potentiate peripheral inflammation, …
Purpose: Dysmenorrhea is a common disorder that substantially disrupts the lives of young women. The frequency of 14 associated symptoms both within and outside the pelvis was determined. Patients and methods: Symptom questionnaires were co…
Many rodent models of endometriosis are invasive, involving surgery to implant donor endometrial tissue into recipient animals. Moreover, few studies have compared and contrasted lesions between rodent strains and estrous stages without exo…
We aimed to develop a questionnaire that assesses the impact of pelvic pain on women, regardless of diagnosis, that has high utility, sound psychometric performance, easy scoring, and high reliability. Two studies, with 3 separate cohorts, …
In the central nervous system, bidirectional signaling between glial cells and neurons ('neuroimmune communication') facilitates the development of persistent pain. Spinal glia can contribute to heightened pain states by a prolonged release…
BACKGROUND: Persistent pelvic pain (PPP) is estimated to affect 15-25% of women. Despite this, few guidelines for management are available and few medical practitioners feel adequately skilled to manage the complex range of symptoms that pr…
Anecdotally, severe dysmenorrhoea can pre-date the development of chronic pelvic pain (CPP). This study describes the timeline for the transition from dysmenorrhoea to CPP in a cohort of new patients attending a private gynaecology clinic. …
ObjectiveTo determine whether accuracy of visual diagnosis of endometriosis at laparoscopy is determined by stage of disease.DesignProspective longitudinal cohort study (Canadian Task Force classification II-2).SettingTertiary referral cent…
With so little research into chronic pelvic pain (CPP) worldwide, current management occurs in a vacuum of knowledge few areas of medicine would accept. No statistical data for the prevalence of CPP in Australia are available, but if CPP is…
aEndometriosis Care Centres Australia, Adelaide, SA 5067, Australia bSchool of Medical Sciences, University of New South Wales Sydney, NSW 2052, Australia *Corresponding author. Tel.: +61 2 9385 2471; fax: +61 2 9385 8016. E-mail: [email pr…