Elizabeth C Corfield

No ORCID on file · 3 papers in corpus · active 2024-2025

Study types

  • other 3

Condition tags

  • endometriosis 3
  • infertility 2
  • irritable_bowel_syndrome 1
other 2025
Genome-wide insights into generalised anxiety using a dimensional symptom severity approach
medRxiv : the preprint server for health sciences ·doi:10.1101/2025.07.10.25331321

We performed a genome-wide association meta-analysis of generalised anxiety symptom severity in 696,563 individuals of European ancestry from 14 cohorts. We identified 82 independent genome-wide significant variants within 76 loci, 41 of wh…

other 2025
Polygenic scores for dizygotic twinning: insights into the genetic architecture of female fertility
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-025-03515-4

PURPOSE: Natural dizygotic twinning (DZT) results from hyper-ovulation and is an indicator of female fertility. However, some traits linked to DZ twinning are also associated with infertility. We examined the relationship between DZT and fe…

other 2024
Polygenic Scores for Dizygotic Twinning: Insights into the Genetic Architecture of Female Fertility
medRxiv : the preprint server for health sciences ·doi:10.1101/2024.12.02.24318308

Natural dizygotic twinning (DZT) results from hyper-ovulation and is considered an indicator of female fertility. DZT has low polygenicity, with only 0.20% of SNPs estimated to have a nonzero effect. A polygenic score (PGS) for DZT explains…