Reynir T Geirsson

No ORCID on file · 4 papers in corpus · active 2005-2018

Study types

  • meta-analysis 2
  • article 1
  • other 1

Condition tags

  • endometriosis 4
meta-analysis 2018
Variants associating with uterine leiomyoma highlight genetic background shared by various cancers and hormone-related traits
Nature communications ·doi:10.1038/s41467-018-05428-6

Uterine leiomyomas are common benign tumors of the myometrium. We performed a meta-analysis of two genome-wide association studies of leiomyoma in European women (16,595 cases and 523,330 controls), uncovering 21 variants at 16 loci that as…

meta-analysis 2017
Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism
Nature communications ·doi:10.1038/ncomms15539

Endometriosis is a heritable hormone-dependent gynecological disorder, associated with severe pelvic pain and reduced fertility; however, its molecular mechanisms remain largely unknown. Here we perform a meta-analysis of 11 genome-wide ass…

other 2016
Common variants upstream of KDR encoding VEGFR2 and in TTC39B associate with endometriosis
Nature communications ·doi:10.1038/ncomms12350

We conducted a genome-wide association scan (GWAS) of endometriosis using 25.5 million sequence variants detected through whole-genome sequencing (WGS) of 8,453 Icelanders and imputed into 1,840 cases and 129,016 control women, followed by …

article 2005
Quantitative DNA perturbations of p53 in endometriosis: analysis of American and Icelandic cases
Fertility and sterility ·doi:10.1016/j.fertnstert.2005.05.031