Lin Z

BackgroundHigh-Intensity Focused Ultrasound (HIFU) is an emerging non-invasive therapy for breast fibroadenoma. However, its efficacy across different breast glandular types, which may influence acoustic energy deposition, remains underexpl…

Endometriosis is a prevalent chronic inflammatory gynecological disorder affecting approximately 10% of reproductive-age women worldwide, characterized by endometrial-like tissue outside the uterine cavity. Ectopic lesion growth tracks clos…

ObjectiveThe aim of this study was to compare the therapeutic efficacy of integrating virtual reality technology with conventional pelvic floor rehabilitation therapy versus conventional therapy alone in postpartum women with myofascial pel…

Adenomyosis (ADM) is a benign condition associated with various gynecological disorders. However, effective treatment options are limited, highlighting the urgent need for novel therapeutic targets. This study identified abnormal activation…

Lysine lactylation (Kla), an emerging post‑translational modification, bidirectionally regulates cell fate decisions through epigenetic reprogramming and the direct modification of key ferroptosis proteins. It drives disease progression or …

BackgroundRecent studies have revealed that the anti-inflammatory properties of vitamin D may play a role in pain regulation. To systematically map the global research landscape on vitamin D and chronic or idiopathic pain from 2000 to 2023,…

IntroductionUlcerative colitis (UC) is a lifelong, chronic inflammatory disorder, characterized by recurrent and diffuse inflammation of the rectal and colonic mucosa. Increasing evidence suggests that impaired mitophagy contributes to immu…

This study aimed to delineate the molecular profile underlying progesterone resistance in atypical endometrial hyperplasia (AEH), a precancerous condition associated with a high risk of malignant transformation. Using a retrospective cohort…

IntroductionChronic endometritis (CE) is regarded as a potential factor contributing to infertility and embryo implantation failure. The cause of CE remains unclear at present, but it might be associated with intrauterine microbial infectio…

Ovarian cancer (OC) remains a highly lethal gynecologic malignancy characterized by substantial molecular heterogeneity and diagnostic challenges. Although many reviews examine specific aspects of OC biology or treatment, few attempt to con…

Endometriosis is caused by the migration of endometrial cells to locations outside the uterine lining. Despite the increasing prevalence of endometriosis, there has been limited research on genetic effects, and its molecular mechanisms rema…

BACKGROUND AND AIMS: Due to its association with various diseases, atherogenic index of plasma (AIP) has garnered increasing attention. Exploration of the relationship between AIP and endometriosis risk has not been thorough. This nationwid…

Liwen Liu,1 Gaosheng Su,1 Jie Rao,1 Juanbao Peng,1 Xiu Lin,2 Yujie Huang,2 Feng Liang,2 Chuanxia Feng,1 Zhong Lin2 1Department of Anesthesia, The Reproductive Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, People’s Republic…

Background and objectivesPrevious studies have reported there were associations between ovarian function and dietary factors, metabolic factors and gut microbiota. However, it is unclear whether causal associations exist. We aimed to explor…

SignificanceGlobally, infertility affects 10-15% of couples, with Fallopian Tube Obstruction (FTO) being a principal cause. Current therapeutic options are inadequate, prompting a demand for effective, less invasive treatments with lower re…

BackgroundThe prognosis of patients with gastric cancer with peritoneal metastasis (GCPM) is exceedingly poor. This study evaluated the efficacy and safety of hyperthermic intraperitoneal chemotherapy (HIPEC) with paclitaxel combined with S…

RATIONALE: Adenomyoma of the broad ligament is rare. Owing to the absence of typical clinical signs and imaging methods, preoperative diagnosis is challenging, and it is mainly diagnosed through surgical pathology. PATIENT CONCERNS: The pat…

Non-invasive liquid biopsy is a promising strategy for ovarian cancer (OC) detection. We evaluated the feasibility and efficacy of a multi-analyte approach combining circulating tumor DNA (ctDNA) detection with protein biomarkers for early …

Pain management in chronic pancreatitis (CP) patients remains a major challenge, largely due to complex and refractory pain. Such pain detrimentally impacts patients by reducing quality of life, limiting daily activities, increasing psychol…

Difficulties in cognitive functioning (e.g., memory, attention) are common in chronic conditions characterized by physical pain, fatigue and depression. Yet investigations in endometriosis are lacking. We aimed to assess: (1) perceived cogn…

INTRODUCTION: Endometriosis is a prevalent chronic gynecological disorder. Globally, endometriosis affects approximately 5-10% of women of reproductive age, leading to symptoms such as dysmenorrhea, chronic pelvic pain, and infertility. Whi…

Background: The stress hyperglycemia ratio (SHR) has emerged as a promising biomarker for assessing stress-induced hyperglycemia (SH) but has not been evaluated in patients with acute pancreatitis (AP). This study investigates the role of t…

ObjectiveThe potential association between rheumatoid arthritis (RA) and cervical cancer risk is still debated and necessitates additional clinical investigations. This study aimed to explore this relationship using Mendelian randomization …