Jiayi Lu

No ORCID on file · 6 papers in corpus · active 2022-2024

Study types

  • article 4
  • erratum 1
  • review 1

Condition tags

  • endometriosis 6
  • infertility 1
erratum 2024
Correction: Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis
Cell death & disease ·doi:10.1038/s41419-024-06613-w
article 2024
PAK5-mediated PKM2 phosphorylation is critical for anaerobic glycolysis in endometriosis
Frontiers of medicine ·doi:10.1007/s11684-024-1069-3

P21-activated kinase 5 (PAK5) belongs to the PAK-II subfamily, which is an important regulator of cell survival, adhesion, and motility. However, the functions of PAK5 in endometriosis remain unclear. Here, PAK5 is strikingly upregulated in…

article 2023
FDX1 enhances endometriosis cell cuproptosis via G6PD-mediated redox homeostasis
Apoptosis : an international journal on programmed cell death ·doi:10.1007/s10495-023-01845-1

Cuproptosis is a new form of programmed cell death, which is associated with the mitochondrial TCA (tricarboxylic acid) cycle. But the functions of cuproptosis in endometriosis progression are still unknown. Here, we find that cuproptosis s…

review 2022
Emerging hallmarks of endometriosis metabolism: A promising target for the treatment of endometriosis
Biochimica et biophysica acta. Molecular cell research ·doi:10.1016/j.bbamcr.2022.119381

Endometriosis, characterized by ectopic endometrium growth in the extrauterine environment, is one of the most notable diseases of the female reproductive system. Worldwide, endometriosis affects nearly 10 % of women in their reproductive y…

article 2022
Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis
iScience ·doi:10.1016/j.isci.2022.105363

Endometriosis is a common chronic condition characterized by abnormal growth of the endometrium outside the uterus. Heat shock transcription factor 1 (HSF1) is a significant regulator of the proteotoxic stress response and plays an essentia…

article 2022
Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis
Cell death & disease ·doi:10.1038/s41419-022-05241-6

Endometriosis (EM) is one of the vanquished wonted causes of chronic pelvic sting in women and is closely associated with infertility. The long-term, complex, systemic, and post-treatment recurrence of EM wreaks havoc on women's quality of …