Christine N Metz
No ORCID on file
· 63 papers in corpus
· active 2002-2026
Study types
- article 30
- other 29
- preprint 3
- review 1
Condition tags
- endometriosis 57
- mesh:D004715 15
- infertility 13
- chronic_pelvic_pain 2
- mesh:D017699 2
- adenomyosis 1
Top journals
Frequent coauthors
article
2026
Quercetin is a naturally occurring flavonoid found in fruits, vegetables, and teas that is widely available as a dietary supplement. Numerous studies have investigated quercetin’s therapeutic potential across a broad range of diseases and c…
other
2026
ABSTRACT: Decidualization of human endometrial stromal cells (ESCs) precedes the successful implantation of a human embryo. Improper decidualization has been reported in numerous conditions associated with infertility, including endometrios…
other
2026
CONTEXT: Low vitamin D levels have been associated with female infertility, but the underlying mechanisms are not understood. OBJECTIVES: To examine vitamin D treatment, in vitro and in vivo, on human endometrial stromal cell (eSC) decidua…
other
2026
BACKGROUND: While there is evidence that vitamin D deficiency is associated with long menstrual cycles, delayed ovulation, and reduced fertility, it is yet unknown if increasing vitamin D levels can regulate menstrual cycles, and thus possi…
article
2025
other
2025
Cellular senescence leads to stable cell cycle arrest and an inflammatory senescence-associated secretory phenotype that varies with stressor and cell type. To mitigate these effects and improve health, senotherapeutics (e.g., senolytics an…
other
2024
BACKGROUND: Patients with endometriosis suffer with chronic pelvic pain and infertility, and from the lack of pharmacologic therapies that consistently halt disease progression. Differences in the endometrium of patients with endometriosis …
preprint
2024
preprint
2023
Abstract Quercetin, a flavonoid with senolytic activity, has attracted great interest as a therapy for fibrotic diseases such as pulmonary fibrosis, a disorder attributed to senescent pulmonary fibroblasts. Interestingly, quercetin has show…
article
2023
INTRODUCTION: Chronic Pelvic Pain (CPP) is a complex, multifaceted condition that affects both women and men. There is limited literature on the cost utilization the healthcare system and CPP patients incur. The purpose of this analysis is …
other
2022
Additional file 10. A reanalysis of endometriosis cases and controls after removal of one subject on hormones. The Log2 odd ratios (OR) with cell subsets enriched in controls (n=9) on the left and cell subsets enriched in cases (n=10) on th…
other
2022
Additional file 10. A reanalysis of endometriosis cases and controls after removal of one subject on hormones. The Log2 odd ratios (OR) with cell subsets enriched in controls (n=9) on the left and cell subsets enriched in cases (n=10) on th…
other
2022
Additional file 11. A reanalysis of stromal cells from endometriosis cases (n=10) and controls (N=9) after removal of one subject on hormones. Not surprisingly, this revised figure shows alterations in the spatial distribution of the UMAP c…
other
2022
Additional file 11. A reanalysis of stromal cells from endometriosis cases (n=10) and controls (N=9) after removal of one subject on hormones. Not surprisingly, this revised figure shows alterations in the spatial distribution of the UMAP c…
other
2022
Additional file 12. Stromal cells exhibit distinguishing gene markers differentially regulated in ME from endometriosis cases (n=11) and controls (n=9). Violin plots of the top 10 genes that distinguish endometriosis cases and controls with…
other
2022
Additional file 12. Stromal cells exhibit distinguishing gene markers differentially regulated in ME from endometriosis cases (n=11) and controls (n=9). Violin plots of the top 10 genes that distinguish endometriosis cases and controls with…
other
2022
Additional file 13. uNK cells exhibit distinguishing gene markers differentially regulated in ME from endometriosis cases and controls. Violin plots of the top 10 genes that distinguish endometriosis cases (n=11) and controls (n=9) in an an…
other
2022
Additional file 13. uNK cells exhibit distinguishing gene markers differentially regulated in ME from endometriosis cases and controls. Violin plots of the top 10 genes that distinguish endometriosis cases (n=11) and controls (n=9) in an an…
other
2022
Additional file 1. Comparison of UMAP plots of ME digests using fresh cells vs. methanol fixation. Virtually identical UMAP plots are observed using either fresh or methanol fixed cells from a single subject. The ME samples were prepared by…
other
2022
Additional file 1. Comparison of UMAP plots of ME digests using fresh cells vs. methanol fixation. Virtually identical UMAP plots are observed using either fresh or methanol fixed cells from a single subject. The ME samples were prepared by…
article
2022
Additional file 2. Markers for UMAP plots of major cell clusters.
article
2022
Additional file 2. Markers for UMAP plots of major cell clusters.
other
2022
Additional file 3. Cell cluster composition of ME is similar when ME is analyzed after enrichment for endometrial tissues and digested or analyzed as digested whole ME. Comparison of UMAP plots is shown for ME samples prepared by tissue enr…
other
2022
Additional file 3. Cell cluster composition of ME is similar when ME is analyzed after enrichment for endometrial tissues and digested or analyzed as digested whole ME. Comparison of UMAP plots is shown for ME samples prepared by tissue enr…
other
2022
Additional file 4. Cell clusters of ME samples distinguish endometriosis cases and symptomatic cases vs. controls. The combined UMAP plot shown in Fig. 1 is split into controls (n = 9), cases (n = 11), and subjects with suggestive symptoms …