William N. Charman

ORCID: 0000-0002-7051-2023 · 5 papers in corpus · active 1993-2007

Study types

  • article 5
article 2007
Evaluation of the Impact of Surfactant Digestion on the Bioavailability of Danazol after Oral Administration of Lipidic Self-Emulsifying Formulations to Dogs
·doi:10.1002/jps.21246
article 2007
Increasing the Proportional Content of Surfactant (Cremophor EL) Relative to Lipid in Self-emulsifying Lipid-based Formulations of Danazol Reduces Oral Bioavailability in Beagle Dogs
·doi:10.1007/s11095-006-9194-z
article 2004
Susceptibility to Lipase-Mediated Digestion Reduces the Oral Bioavailability of Danazol After Administration as a Medium-Chain Lipid-Based Microemulsion Formulation
·doi:10.1023/b:pham.0000036914.22132.cc
article 1993
Absorption of Danazol After Administration to Different Sites of the Gastrointestinal Tract and the Relationship to Single‐ and Double‐Peak Phenomena in the Plasma Profiles
·doi:10.1002/j.1552-4604.1993.tb03921.x

The absorption of danazol (100 mg) after oral or intraintestinal administration to the proximal jejunum or proximal ileum has been studied in healthy female subjects. The extent of danazol absorption after administration as a solubilized gl…

article 1993
Effect of Food and a Monoglyceride Emulsion Formulation on Danazol Bioavailability
·doi:10.1002/j.1552-4604.1993.tb04673.x

The bioavailability of a single 100-mg dose of danazol delivered from the commercial formulation (hard gelatin capsule) and from an experimental lipid emulsion formulation of danazol was studied in 11 healthy female volunteers in both fed a…