Mengdan Zhao

No ORCID on file · 11 papers in corpus · active 2012-2026

Study types

  • article 8
  • other 1
  • peer-review 1
  • review 1

Condition tags

  • endometriosis 10
  • adenomyosis 3
  • infertility 2
  • dysmenorrhea 1
  • chronic_pelvic_pain 1
other 2026
British journal of pharmacology ·doi:10.1111/bph.70360

BACKGROUND AND PURPOSE: Endometriosis is a chronic, hormone-dependent disorder characterized by ectopic implantation of endometrial tissue, often accompanied by pain and infertility. Although the progesterone receptor modulator RU486 is eff…

peer-review 2024
·doi:10.1039/d4tb01755b/v2/response1
review 2024
Journal of materials chemistry. B ·doi:10.1039/d4tb01755b

Endometriosis and adenomyosis are debilitating gynecological conditions that severely affect the quality of life of women. Traditional diagnostic and treatment methods, including laparoscopic surgery and hormonal therapy, face significant l…

article 2024
Acta biomaterialia ·doi:10.1016/j.actbio.2024.09.037
article 2024
Drug delivery and translational research ·doi:10.1007/s13346-024-01661-3

Mifepristone, a progesterone receptor antagonist, was initially used to terminate early pregnancy. As scientific research advanced, it emerged to be effective in the treatment of various tumors and tumor-like conditions such as endometriosi…

article 2022
Frontiers in bioengineering and biotechnology ·doi:10.3389/fbioe.2022.918368

This investigation probed endometriosis treatment using targeted nanoparticles (NPs) to modulate autophagic activity. To that end, a novel form of polymer-based NP gene delivery platform consisting of polyethyleneimine (PEI) conjugated to s…

article 2022
·doi:10.1097/rd9.0000000000000031

Objective: To study the 12-month effects and possible mechanisms of low-dose mifepristone in the treatment of adenomyosis. Methods: Patients included in this retrospective study had painful adenomyosis and previously received 5 mg mifeprist…

article 2021
Drug design, development and therapy ·doi:10.2147/dddt.s323790

INTRODUCTION: Endometriosis (EMs) is associated with severe chronic pelvic pain and infertility and the development of improved EMs treatment options is an ongoing focus. In this study, we investigated the effects of resveratrol on EMs and …

article 2016
International journal of nanomedicine ·doi:10.2147/ijn.s99692

To identify a new drug candidate for treating endometriosis which has fewer side effects, a new polymeric nanoparticle gene delivery system consisting of polyethylenimine-grafted chitosan oligosaccharide (CSO-PEI) with hyaluronic acid (HA) …

article 2012

Angiogenesis is a prerequisite for the formation and development of endometriosis. Pigment epithelium derived factor (PEDF) is a natural inhibitor of angiogenesis. We previously demonstrated a reduction of PEDF in the peritoneal fluid, seru…

article 2012
PloS one ·doi:10.1371/journal.pone.0045223

Angiogenesis is a prerequisite for the formation and development of endometriosis. Pigment epithelium derived factor (PEDF) is a natural inhibitor of angiogenesis. We previously demonstrated a reduction of PEDF in the peritoneal fluid, seru…