Sung Yun Jung — Endo Lab

article 2018

The pathogenic role of estrogen receptor beta drives in endometriosis

·doi:10.1530/endoabs.54.oc5

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

article 2015

Estrogen Receptor β Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis

Cell ·doi:10.1016/j.cell.2015.10.034

Alterations in estrogen-mediated cellular signaling play an essential role in the pathogenesis of endometriosis. In addition to higher estrogen receptor (ER) β levels, enhanced ERβ activity was detected in endometriotic tissues, and the inh…

article 2012

A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis

Nature medicine ·doi:10.1038/nm.2826

Endometriosis is considered to be an estrogen-dependent inflammatory disease, but its etiology is unclear. Thus far, a mechanistic role for steroid receptor coactivators (SRCs) in the progression of endometriosis has not been elucidated. An…