Zhou L

OBJECTIVE: To investigate the clinical efficacy and potential mechanisms of Traditional Chinese Medicine (TCM) combined with High-Intensity Focused Ultrasound (HIFU) in the treatment of adenomyosis, providing evidence-based support for opti…

Abstract Objective To identify risk factors for postoperative pelvic–abdominal infection after total laparoscopic hysterectomy in patients with benign gynecological diseases and to develop and validate a clinically applicable prediction m…

Per- and polyfluoroalkyl substances (PFAS) have been previously associated with polycystic ovary syndrome (PCOS). However, the health effects of emerging PFAS alternatives on PCOS remain unclear. This study aims to examine the associations …

BACKGROUND: Observational studies have reported comorbidity between autoimmune thyroid disease and endometriosis, but whether this reflects a direct causal relationship or shared susceptibility remains unclear. We evaluated the bidirectiona…

BACKGROUND: In clinical practice, the management of luteinizing hormone (LH) levels during controlled ovarian hyperstimulation (COH) with gonadotropin releasing hormone antagonist (GnRH-ant) protocols presents a significant challenge that c…

BACKGROUND: Over 2.5 million cycles in vitro fertilization (IVF) are conducted annually, and numbers are expected to rise with the aging population. The controlled ovarian stimulation (COS) process, key to IVF success, is inherently complex…

The m5C modification is one of the widely occurring modifications on RNA. In recent years, m5C modification on RNA has increasingly become a focal point in cancer research. Nevertheless, investigating scientific and quantitative research on…

BACKGROUND AND OBJECTIVE: Ileal ureter replacement (IUR) is the definitive management approach for extensive ureteral strictures (UrSs). Patients with UrS exhibit poor health-related quality of life (HRQoL). We conducted a long-term, multi-…

BACKGROUND: Low-level sex chromosome mosaicism (SCM; abnormal cell proportion <10%) is frequently detected during preconception karyotype screening, yet its clinical relevance in assisted reproductive technology (ART) remains controversial.…

The risk of placenta accreta spectrum (PAS) associated with in vitro fertilization and embryo transfer (IVF-ET) in the context of mid-trimester pregnancy loss remains unclear. This study aimed to investigate the impact of IVF-ET on the inci…

Müllerian duct anomalies presenting within an inguinal hernia are exceptionally rare in adult women. We report a case of an irreducible inguinal hernia containing a noncommunicating (type III) rudimentary uterine horn with the ipsilateral f…

BACKGROUND: Polycystic ovarian syndrome (PCOS) is a prevalent endocrine disorder in women of reproductive age. Furthermore, the potential risks of long-term use of combined oral contraceptives (COCs) on ovarian reserve function remain uncle…

Uterine infertility is a substantial global health challenge, imposing profound physical and emotional burdens on affected individuals, with endometrial injury being a key contributing factor. In this study, we report that platelet-derived …

BACKGROUND: Recurrent implantation failure (RIF) and recurrent pregnancy loss (RPL) are major causes of pathological early pregnancy, yet their mechanisms remain poorly understood. This study aimed to identify shared molecular mediators and…

BACKGROUND: The relationship between the vascular flow index (VFI) of the endometrium and the pregnancy outcome in the frozen embryo transfer (FET) cycle remains controversial, and there is currently no recommended optimal range for VFI. O…

Endometriosis is a common gynecological disease that can cause pelvic adhesions. Severe adhesions increase the difficulty of surgery, resulting in prolonged operation time, increased intraoperative bleeding, and increased complications such…

BACKGROUND: Compared with overnight insemination, it remains uncertain whether short-term insemination can improve outcomes in poor responders, and few studies have used cumulative live birth rate as the primary endpoint. The study aims to …

Uterine Corpus Endometrial Carcinoma (UCEC) represents a common malignant neoplasm in women, with its prognosis being intricately associated with available therapeutic interventions. In the past few decades, there has been a burgeoning inte…

BACKGROUND: Hyperuricemia (HUA) has become popular globally, being an important risk factor for various metabolic diseases. Elevated serum uric acid (UA) levels cause adverse reproductive outcomes in women with polycystic ovary syndrome und…

PURPOSE: This study aimed to monitor the expression of B-cell translocation gene 2 (BTG2) in granulosa cells of patients undergoing IVF/ICSI with respect blastocyst quality outcomes. METHODS: We recruited 181 women undergoing IVF/ICSI cycl…

RESEARCH QUESTION: Can bioinformatics-driven identification of hub genes in granulosa cells be used to predict oocyte developmental potential in patients with endometriosis (EMS)-related infertility? DESIGN: This was an exploratory cohort …

PURPOSE: Because hearing impairment as an invisible disability is not considered to have serious body image problems, the impact of body image on negative emotions of deaf or hard-of-hearing (DHH) college students has been relatively neglec…

BACKGROUND: The chronic low back pain (cLBP) literature rarely includes comprehensive characterization of demographic and biomedical factors in a large sample of individuals. The University of Pittsburgh Mechanistic Research Center, entitle…

Endometriosis is an estrogen-dependent chronic inflammatory disease which causes dysmenorrhea, chronic pelvic pain, and infertility in women of childbearing age, significantly impacting their quality of life and physical and mental health. …

OBJECTIVE: To evaluate the efficacy and safety of the Peiyu Granules (PYG) compared with placebo on early miscarriage rates among women undergoing embryo transfer. METHODS: A double-blind, parallel-group randomized clinical trial between F…