Chinnery PF

ORCID: 0000-0002-7065-6617 · 1 paper in corpus · active 2001
2001
American journal of human genetics ·doi:10.1086/318190

We measured the proportion of mutant mtDNA (mutation load) in 82 primary oocytes from a woman who harbored the A3243G mtDNA mutation. The frequency distribution of mutation load indicates that random drift is the principal mechanism that de…