Kalloger SE

No ORCID on file · 8 papers in corpus · active 2008-2014

Study types

  • other 2
  • article 1

Condition tags

  • endometriosis 3
other 2014
A functional proteogenomic analysis of endometrioid and clear cell carcinomas using reverse phase protein array and mutation analysis: protein expression is histotype-specific and loss of ARID1A/BAF250a is associated with AKT phosphorylation
BMC cancer ·doi:10.1186/1471-2407-14-120

BACKGROUND: Ovarian cancer is now recognized as a number of distinct diseases primarily defined by histological subtype. Both clear cell ovarian carcinomas (CCC) and ovarian endometrioid carcinomas (EC) may arise from endometriosis and freq…

2013
Biomarker-based ovarian carcinoma typing: a histologic investigation in the ovarian tumor tissue analysis consortium.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology ·doi:10.1158/1055-9965.epi-13-0391

BackgroundOvarian carcinoma is composed of five major histologic types, which associate with outcome and predict therapeutic response. Our aim was to evaluate histologic type assessments across the centers participating in the Ovarian Tumor…

2013
Type-specific cell line models for type-specific ovarian cancer research.
PloS one ·doi:10.1371/journal.pone.0072162

BackgroundOVARIAN CARCINOMAS CONSIST OF AT LEAST FIVE DISTINCT DISEASES: high-grade serous, low-grade serous, clear cell, endometrioid, and mucinous. Biomarker and molecular characterization may represent a more biologically relevant basis …

2011
Claudin 4 Is differentially expressed between ovarian cancer subtypes and plays a role in spheroid formation.
International journal of molecular sciences ·doi:10.3390/ijms12021334

Claudin 4 is a cellular adhesion molecule that is frequently overexpressed in ovarian cancer and other epithelial cancers. In this study, we sought to determine whether the expression of claudin 4 is associated with outcome in ovarian cance…

other 2011
Loss of BAF250a (ARID1A) is frequent in high-grade endometrial carcinomas
The Journal of Pathology ·doi:10.1002/path.2911

Mutation of the ARID1A gene and loss of the corresponding protein BAF250a has recently been described as a frequent event in clear cell and endometrioid carcinomas of the ovary. To determine whether BAF250a loss is common in other malignanc…

article 2010
ARID1A Mutations in Endometriosis-Associated Ovarian Carcinomas
The New England journal of medicine ·doi:10.1056/nejmoa1008433

BACKGROUND: Ovarian clear-cell and endometrioid carcinomas may arise from endometriosis, but the molecular events involved in this transformation have not been described. METHODS: We sequenced the whole transcriptomes of 18 ovarian clear-ce…

2010
Nectin 4 overexpression in ovarian cancer tissues and serum: potential role as a serum biomarker.
American Journal of Clinical Pathology ·doi:10.1309/ajcpgxk0fr4mhihb

Early detection of ovarian cancer is difficult owing to the lack of specific and sensitive tests available. Previously, we found expression of nectin 4 to be increased in ovarian cancer compared with normal ovaries. Reverse transcriptase-po…

2008
Expression of class I histone deacetylases indicates poor prognosis in endometrioid subtypes of ovarian and endometrial carcinomas.
Neoplasia (New York, N.Y.) ·doi:10.1593/neo.08474

Histone deacetylase (HDAC) inhibitors are an emerging class of targeted cancer therapeutics, and little is known about HDAC expression in gynecologic malignancies. Therefore, we tested the hypothesis whether high-level expression of class 1…