Talukdar R
No ORCID on file
· 3 papers in corpus
· active 2011-2025
Background and objectivesChronic pancreatitis (CP) is a fibroinflammatory disease causing functional injury. Abdominal pain is the predominant symptom negatively impacting the quality of life. The Comprehensive Pain Assessment Tool (COMPAT-…
Background & aimsExperimental studies in acute pancreatitis (AP) suggest a strong association of acinar cell injury with cathepsin B-dependent intracellular activation of trypsin. However, the molecular events subsequent to trypsin activati…
Background & aimsThe role of trypsinogen activation in the pathogenesis of acute pancreatitis (AP) has not been clearly established.MethodsWe generated and characterized mice lacking trypsinogen isoform 7 (T7) gene (T(-/-)). The effects of …