Dixit A

No ORCID on file · 5 papers in corpus · active 2016-2022
2022
TRPV1 channel in spermatozoa is a molecular target for ROS-mediated sperm dysfunction and differentially expressed in both natural and ART pregnancy failure.
Frontiers in cell and developmental biology ·doi:10.3389/fcell.2022.867057

Bi-directional crosstalk between Ca2+ signaling and ROS modulates physiological processes as a part of a regulatory circuit including sperm function. The role of transient receptor potential vanilloid 1 (TRPV1) in this regard cannot be unde…

2021
Identification of multipotent drugs for COVID-19 therapeutics with the evaluation of their SARS-CoV2 inhibitory activity.
Computational and structural biotechnology journal ·doi:10.1016/j.csbj.2021.04.014

The SARS-CoV2 is a highly contagious pathogen that causes COVID-19 disease. It has affected millions of people globally with an average lethality of ~3%. There is an urgent need of drugs for the treatment of COVID-19. In the current studies…

2020
Identification of drugs targeting multiple viral and human proteins using computational analysis for repurposing against COVID-19
·doi:10.21203/rs.3.rs-101778/v1

Abstract The SARS-CoV2 is a highly contagious pathogen that causes COVID-19 disease. It has affected millions of people globally with an average lethality of ~3%. Unfortunately, there is no standard cure for the disease, although some drug…

2020
Identification of Drugs Targeting Multiple Viral and Human Proteins Using Computational Analysis for Repurposing Against COVID-19
·doi:10.26434/chemrxiv.12366938.v1

The SARS-CoV2 is a highly contagious pathogen that causes a respiratory disease named COVID-19. The COVID-19 was declared a pandemic by the WHO on 11th March 2020. It has affected about 5.38 million people globally (identified cases as o…

2016
Release of Cathepsin B in Cytosol Causes Cell Death in Acute Pancreatitis.
Gastroenterology ·doi:10.1053/j.gastro.2016.06.042

Background & aimsExperimental studies in acute pancreatitis (AP) suggest a strong association of acinar cell injury with cathepsin B-dependent intracellular activation of trypsin. However, the molecular events subsequent to trypsin activati…