Schindler AE

Endometriosis was induced in 40 mature female rats by means of transplantation of endometrium on the peritoneum near the ovary. Three weeks later, all the rats were laparotomized and they were randomized into four groups according to treatm…

We report on two cases of vaginal bleeding after hysterectomy. These patients suffered from cyclical therapy resistant vaginal bleeding and complaint in the lower abdomen. The final diagnosis and therapy of a vaginal cuff endometriosis made…

A phase III multicentre study was carried out with the GnRH agonist buserelin (Suprecur) at five university institutions (Dept. of Obstetrics and Gynaecology of Essen, Kiel, Tübingen, Münster and Erlangen) to evaluate the effect of Busereli…

This is a case report on an endometriosis in retroperitoneally situated lymphatic nodes in a 29-year-old patient. The patient had a cervical carcinoma FIGO Ib and was treated surgically by radical hysterectomy after Wertheim-Meigs-Okabayash…

30 formalin-fixed and paraffin embedded and 20 fresh frozen samples of endometriotic tissue were analysed immunohistochemically for the concentration of estrogen and progesterone receptors. In the formalin-fixed and paraffin embedded group …

In an open, non-randomized prospective phase-III-study the clinical and endocrine efficacy as well as the safety of leuprorelin acetate depot (Enantone-Gyn Monats-Depot) were investigated. The therapeutic results of 198 patients, gathered f…

27 patients of the department of gynecology and obstetrics of the university of Essen received a six month therapy with the GnRH-analogon triptorelin because of endometriosis diagnosed by laparoscopy. All the patients experienced not only a…

The plasmatic parameters of coagulatory and fibrinolytic activity were studied in 15 patients with biopsy-proven endometriosis treated with leuprorelin acetate for 6 months. Bleeding time remained constant, indicating the absence of increas…

During the past decade, the development of various gonadotrophin-releasing hormone (Gn-RH) agonists, which induce reversible hypo-oestrogenism has opened a new area in the medical management of endometriosis. In an open, multicentre phase I…