Abstract Motivation Knowledge graphs (KGs) are a robust formalism for structuring biomedical knowledge, but large-scale KGs often require complex queries, are difficult for non-experts to explore, and lack real-world context (such as experi…
Labeled Property Graph linking endometriosis related concepts and organochlorine compounds. This graph was extracted using the Kg4j library (v 1.0) from the FORVM knowledge graph and reformatted as a LPG using the Biolink model and the KGX …
Labeled Property Graph linking endometriosis related concepts and organochlorine compounds. This graph was extracted using the Kg4j library (v 1.0) from the FORVM knowledge graph and reformatted as a LPG using the Biolink model and the KGX …
Abstract Study question Do environmental chemicals play a role on deep endometriosis through metabolic disruption? Summary answer The present study support that women with deep endometriosis exhibit a specific metabolic profile associated t…
BACKGROUND: Exposure to persistent organic pollutants (POPs) has been related to the risk of endometriosis however the mechanisms remain unclear. The objective of the present study was to characterize the metabolic profiles underpinning the…
BACKGROUND: -dioxin (TCDD), may play a role in the pathogenesis of endometriosis. OBJECTIVES: ) on the associations between exposure to OCCs and endometriosis-related end points. METHODS: evidence further supported the roles of the aryl hyd…
Humans are exposed daily to complex mixtures of chemical pollutants through their environment and diet, some of which have the potential to disrupt the bodies' natural endocrine functions and contribute to reproductive diseases like endomet…
The greater omentum represents a specific adipose tissue resected with gastric surgery for cancer. Diffuse gastric adenocarcinoma (diffuse-GC) is of major relevance among gastric cancers due to its unknown origin, aggressiveness, and metast…
Endometriosis is a gynaecological disease characterised by the presence of endometriotic tissue outside of the uterus impacting a significant fraction of women of childbearing age. Evidence from epidemiological studies suggests a relationsh…
Background/Aim Endometriosis is a gynaecological disease impacting a staggering 5-15% of women with dramatic socio-economic impacts, aggravated by long diagnostic delays of 8-10 years between symptom onset and surgical confirmation. Previou…
BACKGROUND: Endometriosis is a gynaecological disease characterized by the presence of ectopic endometrial tissue that affects women during their reproductive years, having a strong impact on their lives, fertility and healthcare costs. The…
The gold-standard matrix for measuring the internal levels of persistent organic pollutants (POPs) is the adipose tissue, however in epidemiological studies the use of serum is preferred due to the low cost and higher accessibility. The int…
Endometriosis is a gynaecological disease characterized by the presence of ectopic endometrial tissue. Histologically, it appears as different sub-types, being peritoneal endometriosis, ovarian endometrioma (OvE) and deep infiltrating endom…