Nagendra Monangi

ORCID: 0000-0003-2498-6452 · 3 papers in corpus
lab-animal 2024
A common allele increases endometrial Wnt4 expression, with antagonistic implications for pregnancy, reproductive cancers, and endometriosis
Nature communications ·doi:10.1038/s41467-024-45338-4

The common human SNP rs3820282 is associated with multiple phenotypes including gestational length and likelihood of endometriosis and cancer, presenting a paradigmatic pleiotropic variant. Deleterious pleiotropic mutations cause the co-occ…

review 2024
Recent Advances in Genomic Studies of Gestational Duration and Preterm Birth
Clinics in perinatology ·doi:10.1016/j.clp.2024.02.010

Preterm birth (PTB) is the leading cause of infant mortality and morbidity. For several decades, extensive epidemiologic and genetic studies have highlighted the significant contribution of maternal and offspring genetic factors to PTB. Thi…

lab-animal 2022
A SNP affects Wnt4 expression in endometrial stroma, with antagonistic implications for pregnancy, endometriosis and reproductive cancers
·doi:10.1101/2022.10.25.513653

Abstract The common human single nucleotide polymorphism rs3820282 is associated with multiple phenotypes ranging from gestational length to likelihood of endometriosis and ovarian cancer and can thus serve as a paradigm for a highly pleiot…