Jean Guibourdenche

ORCID: 0000-0003-3968-6890 · 6 papers in corpus
2025
Birth defects reporting and the use of dydrogesterone: a disproportionality analysis from the World Health Organization pharmacovigilance database (VigiBase).
Human reproduction open ·doi:10.1093/hropen/hoae072

Study questionIs there an association between dydrogesterone exposure during early pregnancy and the reporting of birth defects?Summary answerThis observational analysis based on global safety data showed an increased reporting of birth def…

other 2025
Reply: Fetal safety of dydrogesterone: clarifying the role of pharmacovigilance
Human reproduction open ·doi:10.1093/hropen/hoaf031
article 2024
O-146 Serum Progesterone levels do not differ between patients with endometriosis and unaffected patients who conceive after Hormone Replacement Therapy-Frozen Embryo Transfer (HRT-FET) cycles
·doi:10.1093/humrep/deae108.165

Abstract Study question Do endometriosis women who achieve a live birth (LB) after Hormone Replacement Therapy-Frozen Embryo Transfer (HRT-FET) have different transfer-day progesterone levels than controls? Summary answer In women achieving…

article 2024
Progesterone levels do not differ between patients with or without endometriosis/adenomyosis both in those who conceive after hormone replacement therapy-frozen embryo transfer cycles and those who do not
Human Reproduction ·doi:10.1093/humrep/deae114

STUDY QUESTION: Do women with endometriosis who achieve a live birth (LB) after HRT-frozen embryo transfer (HRT-FET) have different progesterone levels on the day of transfer compared to unaffected women? SUMMARY ANSWER: In women achieving…

article 2011
The mTOR/AKT Inhibitor Temsirolimus Prevents Deep Infiltrating Endometriosis in Mice
The American Journal of Pathology ·doi:10.1016/j.ajpath.2011.04.020

Deep infiltrating endometriosis (DIE) is a particular clinical and histological entity of endometriosis responsible for chronic pelvic pain and infertility. Here we characterize the proliferative phenotype of DIE cells, to explore the cellu…

other 2010
Antiproliferative effects of cannabinoid agonists on deep infiltrating endometriosis
The American Journal of Pathology ·doi:10.2353/ajpath.2010.100375

Deep infiltrating endometriosis (DIE) is characterized by chronic pain, hyperproliferation of endometriotic cells and fibrosis. Since cannabinoids are endowed with antiproliferative and antifibrotic properties, in addition to their psychoge…