ObjectiveDetermine whether peritoneal macrophages from women with endometriosis-associated infertility express more inducible nitric oxide synthase (NOS2) and produce more NO than fertile controls.DesignUnblinded clinical study.Patient(s)Ni…
ObjectiveWe tested the hypothesis that menstrual debris from ectopic endometrium is the stimulus responsible for eliciting the peritoneal fluid (PF) inflammation observed in infertile women with endometriosis.Design, setting, patientsThe ex…
Pelvic endometriosis is associated with infertility even in women with few peritoneal implants, who ovulate, and have anatomically patent oviducts. Since peritoneal fluid is in contact with peritoneal endometrial implants as well as with th…
The mechanism of infertility in women with endometriosis is unknown, but it is independent of mechanical factors that affect fallopian tube function. Increased numbers of peritoneal macrophages are present in women with endometriosis and ha…