Wen J

ORCID: 0000-0001-5067-2647 · 31 papers in corpus
other 2015
Clinical and experimental obstetrics & gynecology ·doi:10.12891/ceog1978.2015

BACKGROUND: Endometriosis is a common gynecological disease and exact pathogenesis is still unclear. Recently, an increasing interest has been given to the potential role of stem cells in the development of endometriosis. The aim of this st…

diagnostic-accuracy 2015
Cancer biomarkers : section A of Disease markers ·doi:10.3233/cbm-150457

BACKGROUND: Serous epithelial ovarian cancer is the most common variety of ovarian cancer and is currently diagnosed using serum CA-125 levels. HMGA1 a small 10.6-12 kDa protein, has been implicated as a potentially important tumor biomarke…

observational 2012
Human Reproduction ·doi:10.1093/humrep/des094

BACKGROUND The recently identified human brain-derived neurotrophic factor (BDNF) Val66Met polymorphism was found to be associated with altered susceptibility to some neuropsychiatric disorders. Interestingly, BDNF together with its recepto…

lab-animal 2008
Journal of medicinal chemistry ·doi:10.1021/jm8006454

The discovery of novel uracil phenylethylamines bearing a butyric acid as potent human gonadotropin-releasing hormone receptor (hGnRH-R) antagonists is described. A major focus of this optimization was to improve the CYP3A4 inhibition liabi…

observational 2007
Fertility and sterility ·doi:10.1016/j.fertnstert.2006.11.155

OBJECTIVE: To determine the level of interleukin-1 receptor antagonist (IL-1ra) in peritoneal fluid (PF) and serum in patients with endometriosis. DESIGN: A prospective analytical study. SETTING: University-affiliated obstetrics and gynec…

observational 2006
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences ·doi:10.3785/j.issn.1008-9292.2006.06.014

OBJECTIVE: To investigate whether interleukin-1 beta (IL-1beta ) and interleukin-1 receptor antagonist (IL-1RA) gene polymorphisms are associated with endometriosis (EMs) in Chinese women. METHODS: One hundred and thirty-eight patients wit…