Caroline Wuyts

No ORCID on file · 1 paper in corpus · active 2026

Study types

  • other 1
other 2026
A duo of redox-sensitive pore-loop cysteines controls the activity of the neural ion channel TRPM3
Communications chemistry ·doi:10.1038/s42004-026-01889-9

Transient Receptor Potential Melastatin 3 (TRPM3) is a non-selective, Ca2+-permeable ion channel that plays a pivotal role in peripheral thermosensation and nociception. Moreover, gain-of-function variants in TRPM3 underlie a spectrum of ne…