Robbe Roelens

ORCID: 0009-0002-4458-1700 · 4 papers in corpus · active 2024-2026

Study types

  • other 3
  • review 1
other 2026
Communications chemistry ·doi:10.1038/s42004-026-01889-9

Transient Receptor Potential Melastatin 3 (TRPM3) is a non-selective, Ca2+-permeable ion channel that plays a pivotal role in peripheral thermosensation and nociception. Moreover, gain-of-function variants in TRPM3 underlie a spectrum of ne…

other 2026
Nature communications ·doi:10.1038/s41467-026-71226-0

The transient receptor potential melastatin 3 (TRPM3) channel is a key mediator of peripheral pain signaling, and pathogenic mutations in TRPM3 are linked to neurodevelopmental delay and epilepsy. Despite the therapeutic promise of TRPM3 mo…

other 2026
Cell reports. Medicine ·doi:10.1016/j.xcrm.2026.102645

Trigeminal nerve injury can lead to chronic and difficult-to-treat orofacial neuropathic pain. Here, we uncover a key role for the cation channel TRPM3 in the chronic constriction injury of the infraorbital nerve (IoN-CCI) mouse model of tr…

review 2024
Biochimica et biophysica acta. Molecular cell research ·doi:10.1016/j.bbamcr.2024.119709

Developmental and epileptic encephalopathies (DEE) are a broad and varied group of disorders that affect the brain and are characterized by epilepsy and comorbid intellectual disability (ID). These conditions have a broad spectrum of sympto…