Liu Z

Oxidative stress-induced endometrial injury has been shown to contribute to infertility; however, effective strategies that can simultaneously scavenge reactive oxygen species (ROS) and restore mitochondrial and antioxidant homeostasis rema…

AIM: To systematically assess the prevalence of sexual dysfunction among patients suffering from endometriosis. METHODS: A literature search was carried out using databases such as PubMed, Web of Science, CNKI, and Wanfang from the incepti…

INTRODUCTION: In this exploratory case-control study, we investigated the potential associations of pregnancy-associated plasma protein-A (PAPP-A), β-human chorionic gonadotrophin (β-HCG), vascular endothelial growth factor (VEGF), and leuk…

BACKGROUND: Compared with overnight insemination, it remains uncertain whether short-term insemination can improve outcomes in poor responders, and few studies have used cumulative live birth rate as the primary endpoint. The study aims to …

Adenomyosis is a common gynecological disorder with incompletely understood pathogenesis. Through single-cell RNA sequencing of adenomyosis tissues, we identified epithelial-endothelial transition (EET) as a key pathological mechanism and d…

OBJECTIVE: This work aimed to evaluate the clinical value of serumanti-Müllerian hormone (AMH), follicle-stimulating hormone (FSH), luteinizing hormone (LH), and transvaginal ultrasound (TVU) parameters in the diagnosis of ovarian reserve f…

Endometriosis (EMS) is characterised by a disrupted peritoneal immune microenvironment where M2 macrophage polarization and impaired phagocytosis promote lesion survival. Single-cell RNA-seq (ScRNAseq) of the peritoneal macrophages from EMS…

Postoperative alterations in peritoneal anatomical planes, unclosed mesenteric defects after reimplanted ureter may pose risk of internal hernia. This case report begins with a typical clinical case to present our team's diagnostic and ther…

IntroductionTranscription factor EB (TFEB) deficiency contributes to insufficient autophagic degradation, resulting in zymogen granule (ZG) accumulation and subsequent premature activation, which underlies the pathogenesis of alcoholic panc…

PURPOSE: ARID1A, encoding a component of the switch/sucrose nonfermentable complex, is frequently mutated in urothelial carcinoma. However, its specific impacts on clinical outcomes and CD8+ T-cell functions in urothelial carcinoma remain p…

Repeated implantation failure (RIF) presents a significant challenge to in vitro fertilization (IVF), and abnormalities in the endometrium often play a crucial role in RIF. To enhance and deepen our understanding of tissue context in the en…

The high rate of unexplained female infertility significantly affects public health and women's mental well-being. Research on dietary nutrients' impact on infertility often overlooks vitamin B2. Exploring this vitamin's role could be cruci…

BACKGROUND & OBJECTIVE: To assess the association of assisted reproductive technologies (ART) conception with postpartum hemorrhage (PPH) during the peripartum and postpartum periods. METHODS: Clinical records of 11,497 patients enrolled i…

BACKGROUND: Although azithromycin has demonstrated potential therapeutic efficacy in the treatment of chronic endometritis (CE), comprehensive studies on the optimal timing of administration are lacking. Our study aims to evaluate the impac…

OBJECTIVES: The objective of study was to compare the effects of pelvic myofascial trigger point release and structured pelvic floor muscle training (PFMT) in patients with female sexual dysfunction after vaginal delivery. PATIENTS AND MET…

BACKGROUND: Hysteroscopic septum resection has been a widespread technique throughout the world in women with a septate uterus. The effectiveness of hysteroscopic septum resection before IVF was equivocal. This study aimed to investigate wh…

OBJECTIVE: To evaluate the efficacy and safety of the Peiyu Granules (PYG) compared with placebo on early miscarriage rates among women undergoing embryo transfer. METHODS: A double-blind, parallel-group randomized clinical trial between F…

Fungal biofilms, as self-produced extracellular polymeric substances that resist antifungal agents and immune defense, represent a major cause of treatment failure and recurrent infections. Therefore, it is of great importance to eradicate …

Single and multiple endometrial polyps (EP) are common gynecological conditions with differing recurrence rates, influencing clinical treatment decisions. This study aimed to characterize the reproductive tract microbiome in both subtypes t…

Ovarian cancer (OC) is a deadly disease and lacks a precise marker for diagnosis worldwide. Our previous work has shown the overexpression of flotillin-1 (FLOT1) in OC tissue. To improve diagnostic sensitivity and accuracy, we evaluated the…

BACKGROUND: Polycystic ovary syndrome (PCOS) is a common gynecological disease accompanied by multiple clinical features, including anovulation, hyperandrogenism, and polycystic ovarian morphology, leading to infertility. Formononetin (FMN)…

Hu sheep are renowned for their adaptation to high-temperature, humid environments and their high fecundity. Despite serving as the founder species for sheep breeding in China, the genetic mechanisms underlying these desirable traits and th…

Premature ovarian failure is a prevalent gynecological endocrine disorder with an increasing incidence rate each year, impacting women's physical and mental health. The causes of POF are poorly understood, but genetic, immune, iatrogenic, e…

Levonorgestrel intrauterine-releasing system (LNG-IUS), an intrauterine device, is recommended for patients with adenomyosis; however, it often shows poor outcomes in these patients because of their large uterine size. This prospective stud…

Microscopic cell classification is a fundamental challenge in both clinical diagnosis and biological research. However, existing methods still struggle with the complexity and morphological diversity of cellular images, leading to limited a…