Ross Dobie

No ORCID on file · 2 papers in corpus · active 2022

Study types

  • article 1
  • peer-review 1

Condition tags

  • endometriosis 1
peer-review 2022
Author response: Single-cell RNA sequencing and lineage tracing confirm mesenchyme to epithelial transformation (MET) contributes to repair of the endometrium at menstruation
·doi:10.7554/elife.77663.sa2

In a mouse model of menstruation stromal cells respond to breakdown of the tissue by changing their identity to become epithelial cells that are incorporated into the luminal epithelium which is rapidly 'healed' without scarring.

article 2022
Single-cell RNA sequencing and lineage tracing confirm mesenchyme to epithelial transformation (MET) contributes to repair of the endometrium at menstruation
eLife ·doi:10.7554/elife.77663

The human endometrium experiences repetitive cycles of tissue wounding characterised by piecemeal shedding of the surface epithelium and rapid restoration of tissue homeostasis. In this study, we used a mouse model of endometrial repair and…