Isaac Shaw

ORCID: 0000-0002-5628-0318 · 3 papers in corpus
review 2022
Mechanisms of Scarless Repair at Time of Menstruation: Insights From Mouse Models
Frontiers in reproductive health ·doi:10.3389/frph.2021.801843

The human endometrium is a remarkable tissue which may experience up to 400 cycles of hormone-driven proliferation, differentiation and breakdown during a woman's reproductive lifetime. During menstruation, when the luminal portion of tissu…

lab-animal 2022
Single-cell RNA sequencing and lineage tracing confirm mesenchyme to epithelial transformation (MET) contributes to repair of the endometrium at menstruation
eLife ·doi:10.7554/elife.77663

The human endometrium experiences repetitive cycles of tissue wounding characterised by piecemeal shedding of the surface epithelium and rapid restoration of tissue homeostasis. In this study, we used a mouse model of endometrial repair and…

lab-animal 2021
Single cell RNA sequencing and lineage tracing confirm mesenchyme to epithelial transformation (MET) contributes to repair of the endometrium at menstruation
·doi:10.1101/2021.12.20.473495

ABSTRACT The human endometrium experiences repetitive cycles of tissue wounding characterised by piecemeal shedding of the surface epithelium and rapid restoration of tissue homeostasis. In this study we used a mouse model of endometrial r…