Repeated exposure to the acute proinflammatory environment that follows ovulation at the ovarian surface and distal fallopian tube over a woman's reproductive years may increase ovarian cancer risk. To address this, analyses included indivi…
PURPOSE: An understanding of the etiologic heterogeneity of ovarian cancer is important for improving prevention, early detection, and therapeutic approaches. We evaluated 14 hormonal, reproductive, and lifestyle factors by histologic subty…
ObjectiveTo evaluate the reproductive and lifestyle correlates of a surgically confirmed diagnosis of endometriosis or adenomyosis in a large prospective cohort.DesignCollection of surgical diagnoses of endometriosis and adenomyosis during …
Abstract There is substantial evidence that smoking produces an ‘anti-oestrogen’ effect (Baron 1984). This important consequence of smoking appears to be the end result of a number of metabolic pathways: altered hepatic metabolism of endoge…