Gaarenstroom KN

No ORCID on file · 6 papers in corpus · active 2011-2025
2025
Salpingectomy With Delayed Oophorectomy Versus Salpingo-Oophorectomy in BRCA1/2 Carriers: Three-Year Outcomes of a Prospective Preference Trial.
BJOG : an international journal of obstetrics and gynaecology ·doi:10.1111/1471-0528.18075

ObjectiveTo compare menopause-related quality of life (QoL) after risk-reducing salpingectomy (RRS) versus risk-reducing salpingo-oophorectomy (RRSO) until 3 years of post-surgery.DesignA prospective study (TUBA study) with treatment alloca…

2024
Coronary Artery Calcium Scores After Prophylactic Premenopausal Bilateral Salpingo-Oophorectomy.
JACC. CardioOncology ·doi:10.1016/j.jaccao.2024.09.011

BackgroundPremenopausal risk-reducing salpingo-oophorectomy (RRSO) in women at high familial risk of ovarian cancer leads to immediate menopause. Although early natural menopause is associated with increased cardiovascular disease risk, evi…

2021
Association of Salpingectomy With Delayed Oophorectomy Versus Salpingo-oophorectomy With Quality of Life in BRCA1/2 Pathogenic Variant Carriers: A Nonrandomized Controlled Trial.
JAMA oncology ·doi:10.1001/jamaoncol.2021.1590

ImportanceMost women with a BRCA1/2 pathogenic variant undergo premature menopause with potential short- and long-term morbidity due to the current method of ovarian carcinoma prevention: risk-reducing salpingo-oophorectomy (RRSO). Because …

2018
Folate receptor-α targeted near-infrared fluorescence imaging in high-risk endometrial cancer patients: a tissue microarray and clinical feasibility study.
Oncotarget ·doi:10.18632/oncotarget.23155

ObjectiveDetection and resection of all malignant lesions is pivotal in staging and cytoreductive surgery (CRS) of endometrial cancer (EC). Intraoperative EC detection could be enhanced using OTL-38, a fluorescent-labelled folate receptor-α…

2016
Clinical Use of Cancer Biomarkers in Epithelial Ovarian Cancer: Updated Guidelines From the European Group on Tumor Markers.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society ·doi:10.1097/igc.0000000000000586

ObjectiveTo present an update of the European Group on Tumor Markers guidelines for serum markers in epithelial ovarian cancer.MethodsSystematic literature survey from 2008 to 2013. The articles were evaluated by level of evidence and stren…

2011
Optimization of near-infrared fluorescent sentinel lymph node mapping in cervical cancer patients.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society ·doi:10.1097/igc.0b013e31822b451d

ObjectiveIn early cervical cancer, a total pelvic lymphadenectomy is the standard of care, even though most patients have negative nodes and thus undergo lymphadenectomy unnecessarily. Although the value of sentinel lymph node (SLN) mapping…