Sutovsky M

No ORCID on file · 4 papers in corpus · active 2008-2013

Study types

  • article 1
  • other 1

Condition tags

  • endometriosis 2
  • infertility 1
2013
Semen levels of spermatid-specific thioredoxin-3 correlate with pregnancy rates in ART couples.
PloS one ·doi:10.1371/journal.pone.0061000

Spermatid specific thioredoxin-3 (SPTRX3 or TXNDC8) is a testis/male germ line specific member of thioredoxin family that accumulates in the superfluous cytoplasm of defective human spermatozoa. We hypothesized that semen levels of SPTRX3 a…

2013
Transgenic pig carrying green fluorescent proteasomes.
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.1220910110

Among its many functions, the ubiquitin-proteasome system regulates substrate-specific proteolysis during the cell cycle, apoptosis, and fertilization and in pathologies such as Alzheimer's disease, cancer, and liver cirrhosis. Proteasomes …

other 2010
Neutralizing TIMP1 restores fecundity in a rat model of endometriosis and treating control rats with TIMP1 causes anomalies in ovarian function and embryo development
Biology of reproduction ·doi:10.1095/biolreprod.109.083287

Human and rat endometriotic lesions synthesize and secrete tissue inhibitor of metalloproteinase 1 (TIMP1). More TIMP1 localizes in the ovarian theca in an established rat model for endometriosis (Endo) when compared to surgical controls (S…

article 2008
Reduced Fecundity in Female Rats with Surgically Induced Endometriosis and in Their Daughters: A Potential Role for Tissue Inhibitors of Metalloproteinase 11
Biology of reproduction ·doi:10.1095/biolreprod.108.073411

The cause of reduced fecundity in women with endometriosis is unknown. Expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) by both ectopic and eutopic endometrium reportedly has a role in the p…