Yu Chen

Granulosa cells (GCs) are somatic cells surrounding oocytes within follicles and are essential for folliculogenesis. Pathological changes in GCs are found in several ovarian disorders. Recent reports have indicated that long non-coding RNAs…

Selenium (Se) is an essential trace element for living organisms and plays diverse biological roles. Endometritis is a common reproductive disorder in dairy cows, causing huge economic losses. In this study, we explored the effects of Se on…

UNLABELLED: BACKGROUND: HPV infection is the major pathogenic factor underlying cervical cancer and precancerous lesions. The cervical HPV infection rates in gynaecological outpatients from Hangzhou, China, were studied in the period from …

The progesterone receptor (PR) is a ligand-activated steroid receptor in the nuclear receptor (NR) superfamily of transcription factor. Besides gynecological and obstetrical indications, the involvement/mechanism of PR in many other disease…

Endometriosis is a common type of estrogen‑dependent, gynecological and chronic inflammatory disease. Epigenetics refers to changes in gene expression that occur without altering the DNA sequence or DNA content. Histone modification dominat…

Phytoestrogens, which have a weak estrogenic effect, bind to estrogen receptors (ERs), thereby competing with estradiol, have an antiestrogenic effect on women of reproductive age with high estrogenic level. Herein, we examined the ability …

Objective:To explore the expression of epithelial neutrophil-activating peptide-78(ENA-78) in adenomyosis and the relationship between ENA-78 and the mechanism of ademomyosis.Methods:The expression of ENA-78 in the ectopic and eutopic endom…

OBJECTIVE: To investigate the IL-8 and IL-10 levels in endometriosis and the regulated role of Neiyifang (NYF) on them. METHODS: Animal models with endometriosis after Cummings method was established. IL-8 and IL-10 levels were determined …