Lucia Funghi

No ORCID on file · 6 papers in corpus · active 2015-2017

Study types

  • article 6

Condition tags

  • endometriosis 3
  • die_deep_infiltrating 2
  • adenomyosis 2
  • dysmenorrhea 1
article 2017
Deep Infiltrating Endometriosis and Endometrial Adenocarcinoma Express High Levels of Myostatin and Its Receptors Messenger RNAs
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719117698579

Myostatin is a growth factor member of the transforming growth factor β superfamily, which is known to play major roles in cell proliferation and differentiation. The present study investigated the messenger RNA (mRNA) expression of myostat…

article 2016
Expression of Inflammatory and Neurogenic Mediators in Adenomyosis: A Pathogenetic Role
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719116657192

ObjectiveAdenomyosis is a uterine disorder characterized by dysmenorrhea, dyspareunia, abnormal uterine bleeding, and infertility. Pathogenesis indicates that endometrial cells invade and proliferate within myometrium, and inflammatory medi…

article 2016
Urocortin and corticotrophin-releasing hormone receptor type 2 mRNA are highly expressed in deep infiltrating endometriotic lesions
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2016.07.009

Ovarian endometrioma (OMA) and deep infiltrating endometriosis (DIE) are the most severe forms of endometriosis, but different pathogenetic mechanisms and clinical symptoms distinguish these two forms. Corticotrophin-releasing hormone (CRH)…

article 2015
Expression of microtubule associated protein 2 and synaptophysin in endometrium: high levels in deep infiltrating endometriosis lesions
Fertility and sterility ·doi:10.1016/j.fertnstert.2015.10.024

ObjectiveTo assess whether healthy endometrium, eutopic endometrium, and endometriotic lesions express nerve growth factor (NGF), microtubule-associated protein 2 (MAP-2), and synaptophysin (SYP).DesignMolecular study in tissue extracts.Set…

article 2015
Myostatin, follistatin and activin type II receptors are highly expressed in adenomyosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2015.05.032

ObjectiveTo evaluate the expression pattern of activins and related growth factor messenger RNA (mRNA) levels in adenomyotic nodules and in their endometrium.DesignProspective study.SettingUniversity hospital.Patient(s)Symptomatic premenopa…

article 2015
Naproxen sodium decreases prostaglandins secretion from cultured human endometrial stromal cells modulating metabolizing enzymes mRNA expression
·doi:10.3109/09513590.2015.1115973

Dysmenorrhea, defined as painful cramps occurring immediately before or during the menstrual period, is a common symptom of different gynecological diseases. An acute uterine inflammatory response driven by prostaglandins (PGs) is responsib…