Yan Li

Objective To investigate the expression of vascular endothelial growth factor (VEGF)and tumor necrosis factor-α (TNF-α) in the ectopic endometrium of adenomyoma and their relation with the pathogenesis of adenomyoma.Methods Endometrial spec…

Endometriosis, one of the most frequent diseases in gynecology, is a benign but invasive and metastatic disease. The altered expression of E-cadherin may play an important role in developing endometriosis. In this paper, we discuss the asso…

OBJECTIVE: To investigate mRNA expression of matrix metalloproteinase (MMP-9) and tissue inhibitor of metalloproteinase (TIMP-1) in ectopic endometriosis tissue and uterine endometrium from women with and without endometriosis. METHODS: Th…

Objective: To investigate the cause, pathogenesis and the clinical-pathologic char- acteristics of endometriosis. Method: According to the area of lesion endometriosis is divided into (1) adenomyosis (also named interna endometriosis, IEM )…

Objective To evaluate the effects of conjugated equine estrogens (CEE) in estrogen replacement therapy (ERT) following total abdominal hysterectomy with bilateral salpingo-oophorectomy (TAH with BSO) for the treatment of endometriosis. Meth…

OBJECTIVE: To investigate the association of the matrix metalloproteinases (MMP) 1, 3 promoter single nucleotide polymorphism (SNP) with the susceptibility to endometriosis (EM) and adenomyosis. METHODS: The SNP of the MMP-1 and MMP-3 gene …

Matrix metalloproteinases (MMPs) may contribute to the development of endometriosis. Genetic variations in several MMP promoters may influence the transcription and expression of MMPs. The purpose of the present study was to assess how gene…

Matrix metalloproteinases(MMPs) and tissue inhibitor of metaalloproteinases(TIMPs) can regulate the composition and degration of extracellular matrix,then take part in many physiogical and pathological processes in vivo.They have a periodic…