Mathew Leonardi

OBJECTIVES: Pouch of Douglas (POD) obliteration is a severe consequence of inflammation in the pelvis, often seen in patients with endometriosis. The sliding sign is a dynamic transvaginal ultrasound (TVS) test that can diagnose POD obliter…

We aim to first systematically review and perform a meta-analysis of the diagnostic accuracy of transvaginal ultrasound (TVUS) and magnetic resonance imaging (MRI) and, second, to evaluate the accuracy of various sonographic diagnostic crit…

Defined by the extrauterine growth of estrogen-dependent endometrial-like epithelial and stromal cells, endometriosis is a common gynecological and systemic inflammatory disease affecting approximately 179 million people assigned female at …

Endometriosis is a chronic oestrogen-dependent gynaecological disorder characterized by non-menstrual pelvic pain, infertility and the extrauterine growth of endometrial-like glands and stroma. It has been noted that the eutopic endometrium…

Operative laparoscopy has been regarded as a viable and evidence-based option for endometriosis-related infertility. However, not all studies support this conclusion and the recent synthesis of high-quality randomised controlled trials (RCT…

OBJECTIVE: To review the diagnostic accuracy and determine the optimum imaging modality for the detection of bladder deep endometriosis (DE) in women with a clinical suspicion of endometriosis. METHODS: A systematic review of studies publi…

STUDY QUESTION: Is there an ideal imaging modality for the detection of uterosacral ligaments/torus uterinus (USL), rectovaginal septum (RVS) and vaginal deep endometriosis (DE) in women with a clinical history of endometriosis? SUMMARY AN…

The current approach to treating endometriosis is often inadequate or intolerable for many patients. Until more effective therapies are available, we should aim to maximize the effectiveness of our current options. Optimization may be possi…

OBJECTIVES: To review the accuracy of different imaging modalities for the detection of rectosigmoid deep endometriosis (DE) in women with clinical suspicion of endometriosis, and to determine the optimal modality. METHODS: A search was co…

BACKGROUND: Chronic pelvic pain (CPP) is a common gynaecological condition accounting for 20% of all gynaecological referrals. There are wide ranges of causes with overlapping symptomatology, therefore the management of the condition is a f…

OBJECTIVE: To investigate the agreement of measurements of the three diameters of rectosigmoid deep endometriosis (DE) lesions between presurgical evaluation using transvaginal sonography (TVS) and postsurgical specimen measurement (PSM). …

The study aims to determine the anatomic distribution of DE, provide an epidemiological overview based on advanced transvaginal ultrasound (aTVS), and describe the possible relationship with clinical features obtained with the World Endomet…

This study's objective was to develop a model to predict the need for ureterolysis (i.e. dissection of the ureter) during laparoscopy for endometriosis. Ureterolysis may be considered an advanced laparoscopic procedure not usually performed…

Study objectiveThe aim of this study was to validate temporally and externally the ultrasound-based endometriosis staging system (UBESS) to predict the level of complexity of laparoscopic surgery for endometriosis.DesignA multicenter, inter…

In transverse, this clip shows the right and left ovary both contain an endometrioma and the ovaries are fixed to each other medially, known as “kissing ovaries.” They are densely adherent to an area that also contains bowel deep endometrio…

Large rectal deep endometriosis nodule completely fixed to the fundus of a retroverted, retroflexed uterus, resulting in complete rectouterine pouch obliteration (negative sliding sign).

COVID-19 has led to new obstacles in the care for women with endometriosis. With many centers around the globe temporarily ceasing outpatient appointments, diagnostic imaging for non-acute pelvic pain, surgery for endometriosis, and fertili…