Shan Xu — Endo Lab

2022

Transient and Prolonged Activation of Wnt Signaling Contribute Oppositely to the Pathogenesis of Asherman's Syndrome.

International journal of molecular sciences ·doi:10.3390/ijms23158808

Asherman's Syndrome (AS) is caused by dysfunction of endometrial regenerative ability, which is controlled by adult stem cells and their niche. The Wnt signaling pathway has been demonstrated to be implicated in this process. This study aim…

article 2020

Understanding the regulatory mechanisms of endometrial cells on activities of endometrial mesenchymal stem-like cells during menstruation

Stem cell research & therapy ·doi:10.1186/s13287-020-01750-3

BACKGROUND: The identification of endometrial stem/progenitor cells in a high turnover rate tissue suggests that a well-orchestrated underlying network controls the behaviour of these stem cells. The thickness of the endometrium can grow fr…

article 2016

Characterization of endometrial mesenchymal-like stem cells activity in different endometrial layers and during the menstrual cycle

article 2016

Spatial and temporal characterization of endometrial mesenchymal stem-like cells activity during the menstrual cycle

·doi:10.1016/j.yexcr.2016.11.020

The human endometrium is a highly dynamic tissue with the ability to cyclically regenerate during the reproductive life. Endometrial mesenchymal stem-like cells (eMSCs) located throughout the endometrium have shown to functionally contribut…