Gunaratne PH

No ORCID on file · 5 papers in corpus · active 2009-2013

Study types

  • article 1

Condition tags

  • endometriosis 1
  • infertility 1
2013
Novel MicroRNAs regulating proliferation and apoptosis in uterine papillary serous carcinomas.
Cancer letters ·doi:10.1016/j.canlet.2013.02.043

MicroRNAs (miRNAs) are endogenous, non-coding RNA transcripts that regulate gene expression. Here, we report 175 putative novel miRNAs identified in uterine cancers profiled by Next Generation Sequencing. Our data indicate that one of these…

article 2011
Functional MicroRNA Involved in Endometriosis
Molecular endocrinology (Baltimore, Md.) ·doi:10.1210/me.2010-0371

Endometriosis is a common disease seen by gynecologists. Clinical features involve pelvic pain and unexplained infertility. Although endometriosis is pathologically characterized by endometrial tissue outside the normal uterine location, en…

2010
A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer.
Molecular endocrinology (Baltimore, Md.) ·doi:10.1210/me.2009-0295

MicroRNAs (miRNAs) are small noncoding RNAs that direct gene regulation through translational repression and degradation of complementary mRNA. Although miRNAs have been implicated as oncogenes and tumor suppressors in a variety of human ca…

2010
Discovery of novel microRNAs in female reproductive tract using next generation sequencing.
PloS one ·doi:10.1371/journal.pone.0009637

MicroRNAs (miRNAs) are small non-coding RNAs that mediate post-transcriptional gene silencing. Over 700 human miRNAs have currently been identified, many of which are mutated or de-regulated in diseases. Here we report the identification of…

2009
Expression profiling of microRNAs by deep sequencing.
Briefings in bioinformatics ·doi:10.1093/bib/bbp019

MicroRNAs are short non-coding RNAs that regulate the stability and translation of mRNAs. Profiling experiments, using microarray or deep sequencing technology, have identified microRNAs that are preferentially expressed in certain tissues,…