Yousef Al-Abed

No ORCID on file · 4 papers in corpus · active 2009-2012

Study types

  • article 3
  • other 1

Condition tags

  • endometriosis 4
  • infertility 2
article 2012
Macrophage Migration Inhibitory Factor Antagonist Blocks the Development of Endometriosis In Vivo
PloS one ·doi:10.1371/journal.pone.0037264

Endometriosis, a disease of reproductive age women, is a major cause of infertility, menstrual disorders and pelvic pain. Little is known about its etiopathology, but chronic pelvic inflammation is a common feature in affected women. Beside…

article 2011
Inhibition of macrophage migration inhibitory factor reduces endometriotic implant size in mice with experimentally induced disease.
Journal of endometriosis

Endometriosis is a debilitating disease common in women of reproductive age characterized by pain and infertility. Macrophage migration inhibitory factor (MIF) is a cytokine whose expression is elevated in endometriotic tissue from women wi…

other 2010
Macrophage migration inhibitory factor elicits an angiogenic phenotype in human ectopic endometrial cells and triggers the production of major angiogenic factors via CD44, CD74, and MAPK signaling pathways
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2010-0417

CONTEXT: An active angiogenesis is required for ectopic endometrial tissue growth. Our previous studies led to the identification of macrophage migration inhibitory factor (MIF), which is markedly elevated in active, vascularized, and early…

article 2009
Up-Regulation of Cyclooxygenase-2 Expression and Prostaglandin E2 Production in Human Endometriotic Cells by Macrophage Migration Inhibitory Factor: Involvement of Novel Kinase Signaling Pathways
Endocrinology ·doi:10.1210/en.2008-1088

Cyclooxygenase (COX) is the rate-limiting enzyme in the metabolic conversion of arachidonic acid to prostaglandins (PGs), including prostaglandin E(2) (PGE(2)), a major mediator of inflammation and angiogenesis. Herein, we report that macro…