Marchand P

No ORCID on file · 6 papers in corpus
article 2024
A comprehensive multiplatform metabolomic analysis reveals alterations of 2-hydroxybutyric acid among women with deep endometriosis related to the pesticide trans-nonachlor
The Science of the total environment ·doi:10.1016/j.scitotenv.2024.170678

BACKGROUND: Exposure to persistent organic pollutants (POPs) has been related to the risk of endometriosis however the mechanisms remain unclear. The objective of the present study was to characterize the metabolic profiles underpinning the…

2023
30th Annual GP2A Medicinal Chemistry Conference.
Pharmaceuticals (Basel, Switzerland) ·doi:10.3390/ph16030432

The Group for the Promotion of Pharmaceutical Chemistry in Academia (GP2A) held their 30th annual conference in August 2022 in Trinity College Dublin, Ireland. There were 9 keynote presentations, 10 early career researcher presentations and…

article 2021
Associations between persistent organic pollutants and endometriosis: A multiblock approach integrating metabolic and cytokine profiling
Environment international ·doi:10.1016/j.envint.2021.106926

Humans are exposed daily to complex mixtures of chemical pollutants through their environment and diet, some of which have the potential to disrupt the bodies' natural endocrine functions and contribute to reproductive diseases like endomet…

article 2018
The challenging use and interpretation of circulating biomarkers of exposure to persistent organic pollutants in environmental health: Comparison of lipid adjustment approaches in a case study related to endometriosis
Chemosphere ·doi:10.1016/j.chemosphere.2018.02.120

The gold-standard matrix for measuring the internal levels of persistent organic pollutants (POPs) is the adipose tissue, however in epidemiological studies the use of serum is preferred due to the low cost and higher accessibility. The int…

article 2017
Associations between internal exposure levels of persistent organic pollutants in adipose tissue and deep infiltrating endometriosis with or without concurrent ovarian endometrioma
Environment international ·doi:10.1016/j.envint.2017.08.019

Endometriosis is a gynaecological disease characterized by the presence of ectopic endometrial tissue. Histologically, it appears as different sub-types, being peritoneal endometriosis, ovarian endometrioma (OvE) and deep infiltrating endom…

article 2016
Distribution of persistent organic pollutants in serum, omental, and parietal adipose tissue of French women with deep infiltrating endometriosis and circulating versus stored ratio as new marker of exposure
Environment international ·doi:10.1016/j.envint.2016.08.011

Several studies have assessed the potential role of environmental chemicals in the onset, growth, and/or physiopathology of endometriosis. However, their contour in terms of considered exposure markers remains limited. The present study aim…