Liu Y

ObjectivePolycystic ovary syndrome (PCOS) is a leading cause of female infertility, and early pregnancy outcomes in affected women are affected by multiple interactive factors; however, no well-established predictive tools are available. Th…

The aim of this study was to detect circulating tumor cells (CTCs) in the peripheral blood of patients with cholangiocarcinoma (CCA) using a CTCs sorting technique and to assess the association between CTC counts and patient prognosis. Epit…

IntroductionEpithelial ovarian cancer (EOC) remains the most lethal gynecological malignancy, and accurate prediction of long-term survival remains challenging. This study aimed to evaluate the prognostic associations of prespecified clinic…

BACKGROUND: Early-life exposures may influence long-term reproductive health, but comprehensive population-based evidence remains limited. This study aimed to evaluate the associations between six early-life factors (long-term/recurrent ant…

ObjectiveThe aim of this study was to compare the therapeutic efficacy of integrating virtual reality technology with conventional pelvic floor rehabilitation therapy versus conventional therapy alone in postpartum women with myofascial pel…

ObjectiveEnhanced Recovery After Surgery (ERAS) protocols have been proven to optimize recovery in various surgical disciplines, including gynecologic surgery. However, their impact on laparoscopic hysterectomy for benign conditions remains…

ObjectiveThis retrospective cohort study aimed to evaluate whether a goal-directed weight loss intervention prior to assisted reproductive technology (ART) improves live birth rates compared with immediate in vitro fertilization (IVF) witho…

ObjectiveTo investigate whether prolonged embryo culture increases the risk of gestational diabetes mellitus (GDM) in pregnancies conceived via frozen embryo transfer (FET).Research design and methodsIn this retrospective cohort study, 26 1…

Yiran Liu,1 Siyi Hua,1 Fang Wang,2 Caixia Zhou,3 Guiping Wan,1 Weiwei Tang11Department of Obstetrics and Gynecology, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing…

Adenomyosis is a common gynecological disorder that causes heavy menstrual bleeding and chronic pelvic pain. Progestin-based therapy is widely used for long-term management, but irregular uterine bleeding frequently occurs and severely affe…

BACKGROUND: Tuberculosis (TB) is among the top 10 causes of global death, and patient delay is a key factor causing higher mortality. This study intends to analyze the associated factors with TB patient delay. METHODS: Embase, Cochrane Lib…

Metabolic dysfunction-associated steatotic liver disease (MASLD) has become the most prevalent chronic liver disease worldwide, yet no pharmacological therapy has achieved regulatory approval. Flavonoids, plant-derived polyphenols encompass…

BackgroundNon-neoplastic gynecological diseases substantially impact women of childbearing age (WCBA), contributing to global burden. Despite growing awareness, disparities in healthcare access remain widespread across regions and socioecon…

Premature ovarian insufficiency (POI) is a significant clinical challenge leading to amenorrhea and infertility in young women. While its etiology is complex, recent research has highlighted aberrant protein glycosylation as a novel and cru…

Endometriosis (EMs) is a prevalent, estrogen-dependent gynecological disorder characterized by the ectopic implantation and proliferation of endometrial-like tissue outside the uterine cavity, affecting approximately 10% of reproductive-age…

Abstract Hypoxia, a state of reduced oxygen availability, drives endometrial disease progression by inducing cellular reprogramming that promotes inflammation, angiogenesis, and aberrant cell survival in endometriosis and endometrial cance…

Background: fertilization remains challenging. This study aimed to develop and validate a machine learning model for predicting the cumulative live birth rate in women with endometriomas who underwent alcohol sclerotherapy followed by assis…

BackgroundAmong patients undergoing hysterectomy for benign indications, Black patients experience higher rates of perioperative complications across both abdominal and minimally invasive surgical routes. This disparity persists after adjus…

BackgroundIL20RB, interleukin 20 receptor subunit beta, functions as a cytokine receptor subunit coding gene and has been discovered to serve an essential function in human malignancies. However, the link between IL20RB expression, clinical…

IntroductionRetained products of conception (rPOC) are a common complication following early pregnancy loss (EPL) and may contribute to infertility and delays in subsequent fertility treatment. Oral contraceptive pills (OCPs) are frequently…

Endometriosis is an estrogen-dependent disorder characterized by chronic inflammation, immune dysregulation, and altered hormone metabolism. Although gut microbiota-derived metabolites have been implicated in shaping immune microenvironment…

ObjectiveTo evaluate the impact of adjunctive levonorgestrel-releasing intrauterine device (LNG-IUD) placement on amenorrhea rates and hysterectomy risk following endometrial resection or ablation in women with abnormal uterine bleeding (AU…

BACKGROUND: Adenomyosis (AM) is frequently associated with compromised embryo implantation. The leukemia inhibitory factor (LIF)/signal transducer and activator of transcription 3 (STAT3) signaling pathway is crucial for endometrial recepti…

Gynecological diseases represent a persistent global health burden. According to a WHO report, the global incidence of gynecological diseases exceeds 65%. Furthermore, over 90% of women suffer from gynecological issues to varying degrees. T…

The paradigm shift of lactate from a mere metabolic byproduct to a pleiotropic signaling molecule, coupled with the discovery of lactylation, provides a crucial framework for understanding how metabolic reprogramming drives systemic patholo…