Zhan L

No ORCID on file · 11 papers in corpus · active 2016-2025

Study types

  • other 4
  • review 4
  • article 1

Condition tags

  • endometriosis 9
other 2025
BMC medicine ·doi:10.1186/s12916-025-04395-2
review 2024
BMC medicine ·doi:10.1186/s12916-024-03571-0

BACKGROUND: Endometriosis is well known as a chronic inflammatory disease. The development of endometriosis is heavily influenced by the estrogen receptor β (ERβ), while NOD-like receptors (NLRs) family CARD domain-containing 5 (NLRC5) exhi…

2024
Scientific reports ·doi:10.1038/s41598-024-66153-3

Cervical cancer (CC) is the fourth most common cancer among women worldwide. NLR Family CARD Domain Containing 5 (NLRC5) plays an important role in tumorigenesis. However, its effect and mechanism in CC remains unclear. In this study, we ai…

other 2024
BMC medicine ·doi:10.1186/s12916-024-03415-x
other 2023
Journal of pharmaceutical and biomedical analysis ·doi:10.1016/j.jpba.2022.115198

Elagolix sodium (ELS) is a marketed product using to release moderate to severe endometriosis-associated pain. It contains functional groups such as carboxyl group, secondary amino group, 2,4-dioxo pyrimidinyl and several benzyl or benzyl-l…

review 2023
Frontiers in immunology ·doi:10.3389/fimmu.2023.1161606

Endometriosis is closely associated with ectopic focal inflammation and immunosuppressive microenvironment. Multiple types of pattern recognition receptors (PRRs) are present in the innate immune system, which are able to detect pathogen-as…

2022
Experimental hematology & oncology ·doi:10.1186/s40164-022-00357-z

Uterine and ovarian cancers are the most common gynecologic cancers. N6-methyladenosine (m6A), an important internal RNA modification in higher eukaryotes, has recently become a hot topic in epigenetic studies. Numerous studies have reveale…

other 2020
Frontiers in pharmacology ·doi:10.3389/fphar.2020.01281

Nod-like receptor (NLR) family caspase activation and recruitment domain containing 5 (NLRC5) is a newly identified sub-class of the NLR family. It regulates inflammation and has a key function in innate and adaptive immunologic reactions. …

article 2018
Fertility and sterility ·doi:10.1016/j.fertnstert.2018.06.028

ObjectiveTo investigate the levels of NLRC5 and autophagy in women with leiomyoma and endometriosis and the correlation between NLRC5 level and autophagy level.DesignCase-control study.SettingClinics.Patient(s)Sixty-five patients were recru…

review 2017
Biochemical and biophysical research communications ·doi:10.1016/j.bbrc.2017.10.145

Endometriosis is a chronic, estrogen-dependent disease and characterized by the implantation of endometrial glands and stroma deep and haphazardly into the outside the uterine cavity. It affects an estimated 10% of the female population of …

review 2016
Biochimie ·doi:10.1016/j.biochi.2016.01.006

Endometriosis is a common gynecologic disease defined as the presence of ectopic endometrial tissues on the ovaries and pelvic peritoneum, and it is a significant cause of pelvic pain, dysmenorrhea and infertility of women in their reproduc…