Jin Zhang

Uterine mechanical properties, particularly tissue stiffness, are dynamically regulated during the embryo implantation window to ensure optimal mechanocompatibility. However, maternal aging and fibrotic pathologies, such as adenomyosis and …

Varicocele-induced decline in sperm quality is a common cause of male infertility. While varicocelectomy improves semen parameters, the mechanisms remain unclear. Recent studies suggested that small noncoding RNAs (sncRNAs) in sperm play a …

Adding plant extracts to diets to enhance sow performance and health is widely regarded as a healthy and sustainable practice. In promoting antibiotic-free farming, plant extracts have emerged as a leading solution for enhancing sow fertili…

Analgesia by non-steroidal anti-inflammatory drugs (NSAIDs) is ascribed to inhibition of prostaglandin (PG) biosynthesis and ensuing inflammation. However, NSAIDs have life-threatening side effects, and inhibition of inflammation delays pai…

BACKGROUND: Immunotherapy has emerged as a novel strategy for cancer treatment following surgery, radiotherapy, and chemotherapy. Immune checkpoint blockade and Chimeric antigen receptor (CAR)-T cell therapies have been successful in clinic…

ETHNOPHARMACOLOGICAL RELEVANCE: Reproductive ability of sows is a primary element influencing the development of pig farming. Herbal extracts of Angelica sinensis (Oliv.) Diels, Astragalus mongholicus Bunge, Eucommia ulmoides Oliv., and Pol…

OBJECTIVE: This study aimed to investigate the risk factors of cesarean section and establish a prediction model for cesarean section based on the characteristics of pregnant women. METHODS: The clinical characteristics of 2552 singleton p…

Objective: To investigate the differential expression of microRNA (miRNA) in patients with endometrial cancer and its relationship with prognosis and survival. Method: We used The Cancer Genome Atlas (TCGA) database to analyze differentiall…

Pancreatitis is an inflammatory disease of the pancreas characterized by acinar cell injury and is associated with the abnormal release of trypsin, which results in high mortality due to systemic inflammatory response syndrome (SIRS) and mu…

PROBLEM: Endometriosis (EM) is a chronic immunoinflammatory disease associated with an abnormal immunotolerant microenvironment. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells that play a m…

Considerable correlative evidence suggests an important role for matrix metalloproteinases (MMPs) in menstruation, a pro-cess which occurs naturally in very few species. In this study, MMP expression was examined in a mouse model of endome-…

Objective To compare the effects of Leuprorelin and Marvelon on endometriosis(EM)after laparoscopic surgery.Methods Patients with EM were enrolled and divided into laparoscopic surgery group(CON group),laparoscopic surgery combined with Mar…

Objective To explore the clinical efficacy of drospirenone ethinylestradiol combined with levonorgestrel intrauterine releasing system(LNG-IUS) in the treatment of adenomyosis, and the related hormone level was detected. Methods Patients(15…

BACKGROUND: miRNAs are a group of small RNA molecules regulating target genes by inducing mRNA degradation or translational repression. Aberrant expression of miRNAs correlates with various cancers. Although miR-135a has been implicated in …

BackgroundAlthough endometriosis is a common cause of pelvic pain and infertility, the pathogenesis of the disease remains poorly understood. Several theories have been proposed to explain the mechanisms involved in the development of this …

Background Although endometriosis is a common cause of pelvic pain and infertility, the pathogenesis of the disease remains poorly understood. Several theories have been proposed to explain the mechanisms involved in the development of this…

According to the published articles, the methods of MITUM under USG can be classified into 2 category,(1)Location thermal ablation: The uterus leiomyoma is coagulated into necrosis by physical high temperature that is lead into the leiomyom…

Considerable correlative evidence suggests an important role for matrix metalloproteinases (MMPs) in menstruation, a process which occurs naturally in very few species. In this study, MMP expression was examined in a mouse model of endometr…