Giudice L

No ORCID on file · 14 papers in corpus · active 1996-2025

Study types

  • article 7
  • other 1
  • review 1

Condition tags

  • endometriosis 9
  • dysmenorrhea 3
  • infertility 3
  • dyspareunia 3
  • chronic_pelvic_pain 2
other 2025
bioRxiv : the preprint server for biology ·doi:10.1101/2025.07.21.666016

Endometriosis is a chronic, estrogen-dependent condition affecting over 190 million women globally, characterized by the ectopic presence of endometrial-like tissue that leads to inflammation, pain, and infertility. Despite its prevalence, …

article 2018
Contemporary clinical trials ·doi:10.1016/j.cct.2018.03.002

ObjectiveEndometriosis is a chronic, estrogen dependent condition that affects 5-10% of reproductive aged women and is associated with pelvic pain and infertility. As the approach to therapy shifts from surgical ablation to pharmacological …

article 2018
Obstetrics and gynecology ·doi:10.1097/aog.0000000000002675

OBJECTIVE: To evaluate the efficacy and safety of elagolix, an oral, nonpeptide gonadotropin-releasing hormone antagonist, over 12 months in women with endometriosis-associated pain. METHODS: Elaris Endometriosis (EM)-III and -IV were exten…

2017
Scientific reports ·doi:10.1038/s41598-017-10098-3

Previous transcriptome studies of the human endometrium have revealed hundreds of simultaneously up- and down-regulated genes that are involved in endometrial receptivity. However, the overlap between the studies is relatively small, and we…

review 2015
BioMed research international ·doi:10.1155/2015/130854

Endometriosis is histologically characterized by the displacement of endometrial tissue to extrauterine locations including the pelvic peritoneum, ovaries, and bowel. An important cause of infertility and pelvic pain, the individual and glo…

2014
Human reproduction update ·doi:10.1093/humupd/dmt048

Background'Omics' high-throughput analyses, including genomics, epigenomics, transcriptomics, proteomics and metabolomics, are widely applied in human endometrial studies. Analysis of endometrial transcriptome patterns in physiological and …

article 2013
Fertility and sterility ·doi:10.1016/j.fertnstert.2013.03.026

ObjectiveTo explore the relation between bisphenol A and 14 phthalate metabolites and endometriosis.DesignMatched cohort design.SettingFourteen clinical centers.Patient(s)The operative cohort comprised 495 women undergoing laparoscopy/lapar…

article 2013
Journal of endometriosis and pelvic pain disorders ·doi:10.5301/je.5000157

OBJECTIVE: The aim of this study was to estimate the efficacy of elagolix, an oral gonadotropin-releasing hormone (GnRH) antagonist, for the treatment of endometriosis-associated pelvic pain. METHODS: This was a phase II, randomized, placeb…

2012
Human reproduction (Oxford, England) ·doi:10.1093/humrep/der436

BackgroundAlthough histological dating of endometrial biopsies provides little help for prediction or diagnosis of infertility, analysis of individual endometrial proteins, proteomic profiling and transcriptome analysis have suggested sever…

article 2011

OBJECTIVE: \nTo assess the impact of endometriosis on health-related quality of life (HRQoL) and work productivity. \n \nDESIGN: \nMulticenter cross-sectional study with prospective recruitment. \n \nSETTING: \nSixteen clinical centers in t…

2010
Fertility and sterility ·doi:10.1016/j.fertnstert.2009.08.057

ObjectiveTo determine the human endometrial transcriptome during embryonic implantation.DesignCase report.SettingTertiary fertility center.Patient(s)A 24-year-old woman who inadvertently became pregnant during an endometrial biopsy procedur…

2006
The Journal of clinical investigation ·doi:10.1172/jci27306

We studied the vascular effects of invasive human cytotrophoblasts in vivo by transplanting placental villi to the fifth mammary fat pads or beneath the kidney capsules of Scid mice. Over 3 weeks, robust cytotrophoblast invasion was observe…

article 2005
Fertility and sterility ·doi:10.1016/j.fertnstert.2005.02.059

ObjectiveTo report our experience in patients with previous IVF failures who conceived after laparoscopic treatment of endometriosis.DesignRetrospective case series.SettingTertiary center IVF and endoscopy programs.Patient(s)Infertility pat…

article 1996
Human Reproduction ·doi:10.1093/oxfordjournals.humrep.a019479

This prospective cohort study was carried out in a university-based infertility clinic to determine the profile of insulin-like growth factor binding proteins (IGFBPs) in patients with mild endometriosis and no obvious mechanical factor con…